175136-29-5

Basic information

• Product Name: METHYL 2-(5-METHYL-2-PHENYL-1,3-THIAZOL-4-YL)ACETATE
• Synonyms: BUTTPARK 37\06-82;METHYL 2-(5-METHYL-2-PHENYL-1,3-THIAZOL-4-YL)ACETATE;METHYL (5-METHYL-2-PHENYLTHIAZOL-4-YL)ACETATE;Methyl 2-(5-Methyl-2-phenylthiazol-4-yl)acetate;Methyl (5-methyl-2-phenyl-1,3-thiazol-4-yl)acetate;IGRGQWSVDTYHID-UHFFFAOYSA-N
• CAS NO: 175136-29-5
• Molecular Formula: C₁₃H₁₃NO₂S
• Molecular Weight: 247.31
• Mol File: 175136-29-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 42 °C
• Boiling Point: 381.6 °C at 760 mmHg
• Flash Point: 184.6 °C
• Appearance: /
• Density: 1.197g/cm³
• Vapor Pressure: 5.02E-06mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: METHYL 2-(5-METHYL-2-PHENYL-1,3-THIAZOL-4-YL)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-(5-METHYL-2-PHENYL-1,3-THIAZOL-4-YL)ACETATE(175136-29-5)
• EPA Substance Registry System: METHYL 2-(5-METHYL-2-PHENYL-1,3-THIAZOL-4-YL)ACETATE(175136-29-5)

Safety Data

• Hazardous Substances Data: 175136-29-5(Hazardous Substances Data)

Usage

General Description

Methyl 2-(5-methyl-2-phenyl-1,3-thiazol-4-yl)acetate is a chemical compound with the molecular formula C13H13NO2S. It is a thiazole derivative with a methyl group attached to the thiazole ring. METHYL 2-(5-METHYL-2-PHENYL-1,3-THIAZOL-4-YL)ACETATE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has potential biological activities and is often used in medicinal chemistry research. Methyl 2-(5-methyl-2-phenyl-1,3-thiazol-4-yl)acetate is a versatile compound with a variety of applications in the chemical and pharmaceutical industries.

InChI:InChI=1/C13H13NO2S/c1-9-11(8-12(15)16-2)14-13(17-9)10-6-4-3-5-7-10/h3-7H,8H2,1-2H3

Upstream product

• 2227-79-4 benzenecarbothioamide 
• 105983-77-5 methyl 4-bromo-3-oxopentanoate 

Downstream Products

• 175136-30-8 2-[5-methyl-2-phenyl-1,3-thiazol-4-yl]ethanol 
• 196810-92-1 2(S)-<(2-benzoylphenyl)amino>-3-<4-<2-(5-methyl-2-phenylthiazol-4-yl)ethoxy>phenyl>propionic acid methyl ester 

Relevant articles and documents

Oxazolyl-aryloxyacetic acid derivatives and their use as ppar agonists

Compounds represented by the following (I), and pharmaceutically acceptable salts, solvates and hydrates thereof, wherein R1 is an unsubstituted or substituted aryl, heteroaryl, cycloalkyl, aryl-alkyl, heteroaryl-alkyl or cycloalkyl-alkyl, R2 is H, alkyl or haloalkyl, the polymethylene chain (II), is saturated or may contain a carbon-carbon double bond, while n is 2, 3, 4, W is O or S, Y is an unsubsituted or substituted phenylene, naphthylene or 1, 2, 3, 4 tetrahydronaphthylene, R3 is H, alkyl or haloalkyl. R4 is H, alkyl, haloalkyl or a substituted or unsubstituted benzyl, are useful for modulating a peroxisome proliferator activated receptor, particularly in the treatment of diabetes mellitus.

Substituted oxazoles and thiazoles derivatives as hPPARγ and hPPARα activators

The present invention discloses compounds of formula (I), and tautomeric forms, pharmaceutically acceptable salts, or solvates thereof. Preferably, the compounds of the invention are dual activators of hPPARγ and hPPAR{acute over (α)}.