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175140-70-2

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175140-70-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 175140-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,1,4 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 175140-70:
(8*1)+(7*7)+(6*5)+(5*1)+(4*4)+(3*0)+(2*7)+(1*0)=122
122 % 10 = 2
So 175140-70-2 is a valid CAS Registry Number.

175140-70-2Relevant articles and documents

Corticotropin releasing factor antagonists

-

, (2008/06/13)

Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined in the application, and processes fo

Purin-8-ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists

Beck, James P.,Arvanitis, Argyrios G.,Curry, Matt A.,Rescinito, Joseph T.,Fitzgerald, Larry W.,Gilligan, Paul J.,Zaczek, Robert,Trainor, George L.

, p. 967 - 972 (2007/10/03)

A series of purin-8-ones was prepared and discovered to have excellent binding affinity to the CRH-R1 receptor. Structure-activity studies focused on amine side-chain optimization, urea substitution and pyridyl isostere incorporation. Thus, the highly potent purin-8-ones show promise as a new class of potential anxiolytics and/or antidepressants.

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