175201-58-8 Usage
General Description
2-HYDROXYIMINO-2-[(4-METHYLPHENYL)SULFONYL]ACETONITRILE is a chemical compound with the molecular formula C10H10N2O3S. It is a nitrile derivative containing a sulfonyl group and a hydroxyimino functional group. 2-HYDROXYIMINO-2-[(4-METHYLPHENYL)SULFONYL]ACETONITRILE is often used in organic synthesis and pharmaceutical research for its potential as a building block for the synthesis of various biologically active molecules. Its structure and functional groups provide opportunities for further chemical modifications, making it a valuable intermediate in the development of new compounds with potential pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 175201-58-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,0 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 175201-58:
(8*1)+(7*7)+(6*5)+(5*2)+(4*0)+(3*1)+(2*5)+(1*8)=118
118 % 10 = 8
So 175201-58-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O3S/c1-7-2-4-8(5-3-7)15(13,14)9(6-10)11-12/h2-5,12H,1H3
175201-58-8Relevant articles and documents
Free-radical carbo-oximation of olefins and subsequent radical-ionic cascades
Landais, Yannick,Robert, Frédéric,Godineau, Edouard,Huet, Laurent,Likhite, Nachiket
, p. 10073 - 10080 (2013/11/06)
A sequential carbo-formylation cascade has been developed, involving a free-radical carbo-oximation process, followed by the hydrolysis of the oxime ether. For this purpose, we designed a new SEM O-protected sulfonyl oxime, which enable both rapid radical addition and hydrolysis under mild conditions. The resulting aldehyde-esters were then engaged in various nucleophilic cascades, such as Sakurai allylations or domino-Mukaiyama aldol condensation/ lactonizations. Addition of an amine and TMSCN similarly led after Strecker reaction/lactamization to α-cyano-piperidinones in good overall yield. Finally, a Pictet-Spengler/lactamization sequence was devised, which open a new entry toward the tricyclic core of eburnan alkaloids.
