175340-20-2Relevant articles and documents
Enantioselective synthesis of a pyrrolo-benzothiadiazine derivative S 18986, a new AMPA receptor positive modulator
Desos,Serkiz,Morain,Lepagnol,Cordi
, p. 3003 - 3008 (1996)
Enantioselective reduction of pyrrolo-benzothiadiazine 6 using various chiral reducing agents has been studied and led to efficient synthesis of 8 (S 18986) which was established to be of (S) configuration by single crystal X-ray diffraction analysis. S 18986 is a potent and selective AMPA positive modulator which displays total stereoselectivity, the (R) enantiomer being completely inactive.
Process for the synthesis of (3aS)-5,5-dioxo-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4] benzothiadiazine
-
, (2008/06/13)
Process for the industrial synthesis of (3aS)-5,5-dioxo-2,3,3a,4-tetrahydro-1H-pyrrolo-[2,1-c][1,2,4]benzothiadiazine of formula (I): by enantioselective catalytic hydrogenation of 5,5-dioxo-2,3-dihydro-1H-pyrrolo-[2,1-c][1,2,4]benzothiadiazine.
Heteropolycyclic systems. V
Bernabei,Cameroni,Gamberini,Ferioli
, p. 508 - 516 (2007/10/10)
-