175352-79-1

Basic information

• Product Name: N-(diphenylmethylene)-3-trifluoromethylbenzenemethanamine
• Synonyms: N-(diphenylmethylene)-3-trifluoromethylbenzenemethanamine
• CAS NO: 175352-79-1
• Molecular Weight: 339.36
• Mol File: 175352-79-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(diphenylmethylene)-3-trifluoromethylbenzenemethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(diphenylmethylene)-3-trifluoromethylbenzenemethanamine(175352-79-1)
• EPA Substance Registry System: N-(diphenylmethylene)-3-trifluoromethylbenzenemethanamine(175352-79-1)

Safety Data

• Hazardous Substances Data: 175352-79-1(Hazardous Substances Data)

Upstream product

• 1013-88-3 Benzophenone imine 
• 2740-83-2 3-(TRIFLUOROMETHYL)BENZYLAMINE 

Relevant articles and documents

A convenient diastereoselective synthesis of β-aryl-β-aminoalcohols

β-Aryl-β-aminoalcohols (1) were prepared from N-diphenylmethylene benzylamines (2) diastereoselectively in a one-pot procedure.

Diastereoselective and Enantiospecific Synthesis of 1,3-Diamines via 2-Azaallyl Anion Benzylic Ring-Opening of Aziridines

The 1,3-diamine motif appears in numerous complex molecules, yet there are few methods for the stereoselective construction of this moiety. Herein, we demonstrate a stereocontrolled synthesis of 1,3-diamines, which bear up to three contiguous stereogenic centers, through benzylic ring-opening of aziridines with 2-azaallyl anion nucleophiles. Reactions proceed efficiently (yield up to 95%), diastereoselectively (dr up to >20:1), site selectively, and enantiospecifically to deliver products with differentiated amino groups.