175543-32-5

Basic information

• Product Name: {5-[4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-(tert-butyl-dimethyl-silanyloxy)-butylcarbamoyl]-pentyl}-carbamic acid 9H-fluoren-9-ylmethyl ester
• CAS NO: 175543-32-5
• Molecular Weight: 857.175
• Mol File: 175543-32-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {5-[4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-(tert-butyl-dimethyl-silanyloxy)-butylcarbamoyl]-pentyl}-carbamic acid 9H-fluoren-9-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {5-[4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-(tert-butyl-dimethyl-silanyloxy)-butylcarbamoyl]-pentyl}-carbamic acid 9H-fluoren-9-ylmethyl ester(175543-32-5)
• EPA Substance Registry System: {5-[4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-(tert-butyl-dimethyl-silanyloxy)-butylcarbamoyl]-pentyl}-carbamic acid 9H-fluoren-9-ylmethyl ester(175543-32-5)

Safety Data

• Hazardous Substances Data: 175543-32-5(Hazardous Substances Data)

Upstream product

• 175543-31-4 [4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-(tert-butyl-dimethyl-silanyloxy)-butyl]-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 175543-30-3 {4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-hydroxy-butyl}-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 88574-06-5 6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}hexanoic acid 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Relevant articles and documents

New non nucleosidic phosphoramidite reagent for solid phase synthesis of biotinylated oligonucleotides

The synthesis of a 4-N-(6-aminohexanoyl)-4-amino-1,3-butanediol backbone functionalized with a protected biotin moiety is described. The CE phosphoramidite building block was used to incorporate the reporter group into a synthetic probe during solid phase synthesis. The ability of the modified oligomers to form DNA duplex structures with their target sequences and the stability of these structures was measured. Finally, the addition of an extra dT at the 5'-end allowed an efficient 5'-end 32P labelling of the biotinylated oligomers.