17563-12-1

Basic information

• Product Name: 2-(2,3-dihydro-1H-inden-1-ylidene)-2,3-dihydro-1H-inden-1-one
• Synonyms: 2-(2,3-dihydro-1H-inden-1-ylidene)-2,3-dihydro-1H-inden-1-one
• CAS NO: 17563-12-1
• Molecular Weight: 246.309
• Mol File: 17563-12-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(2,3-dihydro-1H-inden-1-ylidene)-2,3-dihydro-1H-inden-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,3-dihydro-1H-inden-1-ylidene)-2,3-dihydro-1H-inden-1-one(17563-12-1)
• EPA Substance Registry System: 2-(2,3-dihydro-1H-inden-1-ylidene)-2,3-dihydro-1H-inden-1-one(17563-12-1)

Safety Data

• Hazardous Substances Data: 17563-12-1(Hazardous Substances Data)

Upstream product

• 83-33-0 inden-1-one 
• 501-52-0 3-Phenylpropionic acid 

Relevant articles and documents

A systematic investigation of long-range couplings in the 1H NMR spectra of dimeric indanones

During the synthesis of methyl substituted indanones by intramolecular cyclization of 3-phenyl-propionic acids, dimerization led to by-products which can be considered as dimeric indanones. The proton NMR spectra of these compounds exhibit pronounced scalar couplings over up to seven bonds. A series of structures of the above type were investigated, and their NMR spectroscopic behaviour is discussed.

Synthesis of 1-indanones by intramolecular Friedel-Crafts reaction of 3-arylpropionic acids catalyzed by Tb(OTf)3

Intramolecular Friedel-Crafts acylation reaction of 3-arylpropionic acids was efficiently catalyzed by Tb(OTf)3 at 250°C to give 1-indanones. Even deactivated 3-arylpropionic acids with halogen atoms on the aromatic ring can be cyclized in moderation to good yields.