1757-72-8

Basic information

• Product Name: 1-Methyl-2-phenylindole-3-carboxaldehyde
• Synonyms: METHYL-2-PHENYL-3-FORMYLINDOLE;1-METHYL-2-PHENYLINDOLE-3-CARBOXALDEHYDE;1-METHYL-2-PHENYLINDOLE-3-CARBOXYALDEHYDE;1-METHYL-2-PHENYLINDOL-3-FORMALDEHYDE;1-METHYL-2-PHENYL-1H-INDOLE-3-CARBALDEHYDE;1-METHYL-2-PHENYL-3-FORMYL INDOLE;3-FORMYL-1-METHYL-2-PHENYLINDOLE;N-Methyl-2-Phenylindole-3-Carboxaldehyde
• CAS NO: 1757-72-8
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.28
• EINECS: 217-149-4
• Product Categories: Intermediates of Dyes and Pigments;Indole;Indoles;Heterocycle-Indole series
• Mol File: 1757-72-8.mol
• Article Data: 27

Chemical Properties

• Melting Point: 128 °C
• Boiling Point: 447.4 °C at 760 mmHg
• Flash Point: 224.4 °C
• Appearance: /
• Density: 1.11 g/cm³
• Vapor Pressure: 3.38E-08mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: 1-Methyl-2-phenylindole-3-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2-phenylindole-3-carboxaldehyde(1757-72-8)
• EPA Substance Registry System: 1-Methyl-2-phenylindole-3-carboxaldehyde(1757-72-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 1757-72-8(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C16H13NO/c1-17-15-10-6-5-9-13(15)14(11-18)16(17)12-7-3-2-4-8-12/h2-11H,1H3

Upstream product

• 3558-24-5 1-methyl-2-phenyl-1H-indole 
• 68-12-2 N,N-dimethyl-formamide 
• 93-61-8 N-methyl-N-phenylformamide 
• 25365-71-3 2-phenyl-1H-indol-3-carboxaldehyde 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 215806-20-5 1-(N-Methyl-2'-phenylindol-3-yl)hex-1-ene 
• 215806-19-2 1-(N-Methyl-2'-phenylindol-3-yl)oct-1-ene 
• 948-65-2 2-phenyl-indole 
• 62-53-3 aniline 
• 70-11-1 α-bromoacetophenone 
• 10257-92-8 2-phenyl-3-methyl-1H-indole 
• 123-39-7 N-Methylformamide 

Downstream Products

• 113751-35-2 4-(1-methyl-2-phenyl-indol-3-ylmethylene)-2-phenyl-4H-oxazol-5-one 
• 122631-44-1 (E)-1-methyl-3-(2-nitrovinyl)-2-phenyl-1H-indole 
• 102311-49-9 2-cyano-3-(1-methyl-2-phenyl-indol-3-yl)-acrylic acid ethyl ester 
• 78395-78-5 1-methyl-2-phenyl-3-hydroxymethylindole 
• 122631-46-3 1-methyl-3-(2-methyl-2-nitrovinyl)-2-phenylindole 
• 82946-83-6 3-(hydroxyphenylmethyl)-1-methyl-2-phenylindole 
• 78395-75-2 3-(4-nitrophenyldiazenyl)-1-methyl-2-phenyl-1H-indole 
• 4677-15-0 1-methyl-2-phenyl-3-(2-benoylvinyl)indole 
• 78602-05-8 1-methyl-2-phenyl-1H-indol-3-yl benzoate 
• 31521-57-0 3-formyl-1-methyl-2-phenyl-5-nitroindole 
• 78395-71-8 1-methyl-2-phenyl-3-nitro-1H-indole 
• 83958-16-1 5-Chloro-3-ethyl-2-[(Z)-2-(1-methyl-2-phenyl-1H-indol-3-yl)-vinyl]-benzothiazol-3-ium; iodide 
• 83958-15-0 5-Bromo-3-ethyl-2-[(Z)-2-(1-methyl-2-phenyl-1H-indol-3-yl)-vinyl]-benzooxazol-3-ium; iodide 
• 83958-17-2 3-Ethyl-2-[(Z)-2-(1-methyl-2-phenyl-1H-indol-3-yl)-vinyl]-6-selenocyanato-benzothiazol-3-ium; bromide 

Relevant articles and documents

Cu/Fe-cocatalyzed meyer-schuster-like rearrangement of propargylic amines: Direct access to e -β-aminoacryaldehydes

A simple and efficient method for the synthesis of β-aminoacryaldehydes via Cu(OAc)2·H2O and FeCl3 cocatalyzed Meyer-Schuster-Like rearrangement of propargylic amines was developed. The reactions proceed selectively as the E-isomers in generally good yields under aerobic conditions, and are compatible with a broad range of functional groups. This method combines C-N bond cleavage as well as the N-aryl group migration and provides a practical and mild synthetic approach to α,β-unsaturated carbonyl compounds, which are useful precursors in a variety of functional group transformations.

COMPOSITION FOR ORGANIC LIGHT EMITTING DIODE ENCAPSULATION AND ORGANIC LIGHT EMITTING DIODE DISPLAY MANUFACTURED THEREFROM

Provided are: a composition for an organic light emitting diode comprising an indole-based photocurable monomer, a non-indole-based photocurable monomer, and an initiator, and an organic light emitting display manufactured therefrom.

Electrochemically Enabled C3-Formylation and -Acylation of Indoles with Aldehydes

Reported herein is an effective strategy for oxidative cross-coupling of indoles with various aldehydes. The strategy is based on a two-step transformation via a well-known Mannich-type reaction and a C-N bond cleavage for carbonyl introduction. The key step - the C-N bond cleavage of the Mannich product - was enabled by electrochemistry. This strategy (with over 40 examples) ensures excellent functional-group tolerance as well as late-stage functionalization of pharmaceutical molecules.