17572-78-0

Basic information

• Product Name: Benzenemethanol, a-(3-phenyl-2-propynyl)-
• Synonyms: 1,4-Diphenyl-3-butin-1-ol;1,4-diphenyl-3-butyn-1-ol;1,4-Diphenyl-but-3-yn-1-ol
• CAS NO: 17572-78-0
• Molecular Formula: C16H14O
• Molecular Weight: 222.287
• Mol File: 17572-78-0.mol
• Article Data: 21

Chemical Properties

• Melting Point: 55-56 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
• Boiling Point: 157-161 °C(Press: 0.2 Torr)
• Density: 1.12±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzenemethanol, a-(3-phenyl-2-propynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-(3-phenyl-2-propynyl)-(17572-78-0)
• EPA Substance Registry System: Benzenemethanol, a-(3-phenyl-2-propynyl)-(17572-78-0)

Safety Data

• Hazardous Substances Data: 17572-78-0(Hazardous Substances Data)

Upstream product

• 96-09-3 styrene oxide 
• 536-74-3 phenylacetylene 
• 4440-01-1 lithium phenylacetylide 
• 100-52-7 benzaldehyde 
• 591-50-4 iodobenzene 
• 1743-36-8 1-phenylbut-3-yn-1-ol 
• 73513-15-2 (3-iodo-1-propyn-1-yl)benzene 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 420121-38-6 methyl (3-phenylprop-2-yn-1-yl) carbonate 
• 82490-61-7 3-phenyl-2-propyn-1-yl methanesulfonate 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 37559-19-6 3-(phenyl)prop-2-yn-1-yl benzoate 

Downstream Products

• 959-27-3 (Z)-1,4-diphenylbut-2-ene-1,4-dione 
• 17572-79-1 1,4-Diphenyl-3-butyn-1-one 
• 1644562-96-8 4,4-diphenyl-3-(trifluoromethyl)but-3-enal 
• 107487-41-2 4-hydroxy-1,4-diphenylbutan-1-one 
• 5604-61-5 4-ethoxy-1,4-diphenylbutan-1-one 
• 1004852-57-6 2,5-diphenyl-3-(phenylselanyl)furan 

Relevant articles and documents

Distal Alkenyl C-H Functionalization via the Palladium/Norbornene Cooperative Catalysis

A distal-selective alkenyl C-H arylation method is reported through a directed palladium/norbornene (Pd/NBE) cooperative catalysis. The key is to use an appropriate combination of the directing group and the NBE cocatalyst. A range of acyclic and cyclic c

Alkynylation of aldehydes mediated by zinc and allyl bromide: a practical synthesis of propargylic alcohols

Abstract: A practical synthesis of propargylic alcohols was developed by alkynylation of aldehydes mediated by zinc and allyl bromide. Aromatic, aliphatic and vinyl aldehydes react with phenylacetylene or 1-hexyne to obtain various propargylic alcohols at room temperature in up to 98% yield. This method is characterized with inexpensive materials, wide substrate scope, and mild reaction conditions, and is also easy to scale up. In addition, this protocol is applicable to the alkynylation of α-ketone esters and epoxides to generate α-tertiary-hydroxy esters and α-alkynyl alcohols, respectively. Graphical Abstract: [Figure not available: see fulltext.].

Rhodium(III)-catalyzed oxidative bicyclization of 4-arylbut-3-yn-1-amines with internal alkynes through C-H functionalization

A new Rh(III)-catalyzed oxidative bicyclization through C-H functionalization is presented. This reaction allows the selective assembly of diverse benzo[g]indoles from 4-arylbut-3-yn-1-amines and internal alkynes via a sequence of aromatic C(sp2)-H functionalization, cyclodimerization and nucleophilic cyclization.