17576-35-1 Usage
General Description
1,3,3-Trimethoxypropene is a chemical compound primarily used in organic synthesis. This substance with a formula of C6H12O3 belongs to the organic class of compounds called acetals which are made up of two distinct alkoxy (OR) groups directly attached to the same carbon atom. It is slightly soluble in water, readily soluble in organic solvents, and has a heavy, fruity, and floral taste or smell. As part of its safety precautions, it is not classified as a dangerous or hazardous substance and considered low in toxicity. However, it may cause eye, skin and respiratory tract irritation on direct contact or inhalation.
Check Digit Verification of cas no
The CAS Registry Mumber 17576-35-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,5,7 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 17576-35:
(7*1)+(6*7)+(5*5)+(4*7)+(3*6)+(2*3)+(1*5)=131
131 % 10 = 1
So 17576-35-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H12O3/c1-7-5-4-6(8-2)9-3/h4-6H,1-3H3
17576-35-1Relevant articles and documents
Claisen Orthoester Rearrangement in the Direct Preparation of Z-Isositsirikine and Z-Geissoschizine Derivatives Possessing the Right Oxidation State at C-17
Lounasmaa, Mauri,Hanhinen, Pirjo,Jokela, Reija
, p. 8623 - 8648 (1995)
The Claisen orthoester rearrangement utilizing allylic alcohol 1 (or 2) and trimethyl 3-methoxyorthopropionate 13a leads to Z-isositsirikine derivatives 21a-22a (or 23a-24a) possessing one RO-function at C-17.In the cases of trialkyl 3,3-dialkoxyorthopropionates , the intermediate ketene acetals 25a,b do not rearrange according to the Claisen mechanism to form compounds 26a,b and/or possessing two two RO-functions at C-17.Syntheses of the intermediate orthoesters, trimethyl 3-methoxyorthopropionate 13a, trimethyl 3,3-dimethoxyorthopropionate 14a, trimethyl trans-3-methoxyorthoacrylate 20c, and triethyl 3,3-diethoxyorthopropionate 14b are described.