17583-14-1

Basic information

• Product Name: 2-Methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one
• Synonyms: 2-Methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one
• CAS NO: 17583-14-1
• Molecular Formula: C₈H₉NOS
• Molecular Weight: 167.22816
• Mol File: 17583-14-1.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one(17583-14-1)
• EPA Substance Registry System: 2-Methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one(17583-14-1)

Safety Data

• Hazardous Substances Data: 17583-14-1(Hazardous Substances Data)

Upstream product

• 932-23-0 2-chloro-cyclohexane-1,3-dione 
• 62-55-5 thioacetamide 
• 60060-44-8 2-bromocyclohexane-1,3-dienone 
• 504-02-9 1,3-cylohexanedione 

Downstream Products

• 33708-23-5 4,6-(Z,E)-dibenzylidene-2-methyl-5,6-dihydro-4H-benzothiazol-7-one 
• 14366-03-1 2-methyl-6-phenyl-4,5-dihydro-thiazolo[4,5-c]acridine 
• 33082-03-0 2-methyl-4,5,6,7-tetrahydro-benzothiazole 
• 827598-56-1 2-methyl-7-oxo-4,5,6,7-tetrahydro-benzothiazole-6-carbaldehyde 
• 1312412-60-4 (E)-2-styryl-5,6-dihydrobenzo[d]thiazol-7(4H)-one 

Relevant articles and documents

Versatile approaches to a library of building blocks based on 5-acylthiazole skeleton

Thiazole derivatives represent an important class of azole heterocycles with a broad spectrum of biological activity and, therefore, the synthesis of these compounds is of remarkable concern. We present here practical and reliable protocol for synthesis of some 5-acylthiazoles and demonstrate their utility in the preparation of several new series of thiazole-containing building blocks through transformation of 5-acyl function. Specifically, thiazole-based alcohols, oximes, primary, and secondary amines were successively synthesized in good to excellent yields. The chemical structures of obtained compounds were confirmed by 1H and 13C NMR-spectroscopy, elemental analysis, and mass-spectrometry.

TMSCl Promoted Direct sp3 C-H Alkenylation to Construct (E)-2-Styryl-tetrahydrobenzo[d]thiazoles

A high-efficient and stereo-specific approach for the preparation of biologically important (E)-2-styryl-tetrahydrobenzo[d]thiazoles has been developed via TMSCl promoted direct sp3 C-H alkenylation of 2-methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-

MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.