175853-25-5Relevant articles and documents
Fused tricyclic β-lactams via intramolecular aryl radical cyclization
Banik, Bimal K.,Subbaraju, Gottumukkala V.,Manhas, Maghar S.,Bose, Ajay K.
, p. 1363 - 1366 (1996)
Easy access to fused tricyclic β-lactams starting with o-bromobenzaldehyde and allyl amine has been devised using intramolecular aryl radical cyclization under the influence of tributyltin hydride. The major product resulted from exo cyclization leading to the formation of a 6-membered ring and thus a tricyclic β-lactam. In some cases, a minor product was a 7-membered ring-containing tricyclic β-lactam formed by endo cyclization.