176-25-0

Basic information

• Product Name: 1,6-Dioxaspiro[4.4]nonane
• Synonyms: 1,6-Dioxaspiro[4.4]nonane
• CAS NO: 176-25-0
• Molecular Formula: C7H12O2
• Molecular Weight: 128.169
• Mol File: 176-25-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 175.6°Cat760mmHg
• Flash Point: 58°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 1.53mmHg at 25°C
• Refractive Index: 1.476
• CAS DataBase Reference: 1,6-Dioxaspiro[4.4]nonane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-Dioxaspiro[4.4]nonane(176-25-0)
• EPA Substance Registry System: 1,6-Dioxaspiro[4.4]nonane(176-25-0)

Safety Data

• Hazardous Substances Data: 176-25-0(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Faint

Usage

Solvent in chemical reactions and organic synthesis

Structural feature

Unique spiro structure with two oxygen atoms linked to the same carbon atom

Reactivity

Special properties and reactivity in organic chemistry

Applications

Reactant in the production of pharmaceuticals, flavor and fragrance compounds, and a precursor for the synthesis of other organic compounds

Safety concerns

Harmful if inhaled, swallowed, or in contact with the skin

Environmental risk

May pose a risk to the environment

InChI:InChI=1/C7H12O2/c1-3-7(8-5-1)4-2-6-9-7/h1-6H2

Upstream product

• 96-48-0 4-butanolide 
• 623-30-3 3-furan-2-yl-propenal 
• 26908-23-6 3-furan-2-yl-propan-1-ol 
• 4543-51-5 3-(2-furyl)propionaldehyde 
• 5694-96-2 3-<2-(3-hydroxypropyl)<1,3>dioxolan-2-yl>propan-1-ol 
• 104-15-4 toluene-4-sulfonic acid 
• 21710-83-8 2-methoxy-1,6-dioxaspiro<4.4>-3-nonene 
• 90953-88-1 α-(2-hydroxyethyl)-β-oxocyclopropanepropionic acid γ-lactone 
• 823-22-3 5-hexanolide 
• 7647-01-0 hydrogenchloride 
• 39511-08-5 (E)-3-(2-furanyl)-2-propenal 
• 64-17-5 ethanol 
• 943643-06-9 3-(butyltellanyl)propan-1-ol 
• 6317-49-3 4-oxopimelate 

Downstream Products

• 89774-18-5 1,7-Dibromo-4-heptanone 
• 40624-07-5 1,7-dichloro-4-heptanone 

Relevant articles and documents

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An Intramolecular Iodine-Catalyzed C(sp3)?H Oxidation as a Versatile Tool for the Synthesis of Tetrahydrofurans

The formation of ubiquitous occurring tetrahydrofuran patterns has been extensively investigated in the 1960s as it was one of the first examples of a non-directed remote C?H activation. These approaches suffer from the use of toxic transition metals in overstoichiometric amounts. An attractive metal-free solution for transforming carbon-hydrogen bonds into carbon-oxygen bonds lies in applying economically and ecologically favorable iodine reagents. The presented method involves an intertwined catalytic cycle of a radical chain reaction and an iodine(I/III) redox couple by selectively activating a remote C(sp3)?H bond under visible-light irradiation. The reaction proceeds under mild reaction conditions, is operationally simple and tolerates many functional groups giving fast and easy access to different substituted tetrahydrofurans.

CHIRAL IMIDODIPHOSPHATES AND DERIVATIVES THEREOF

The invention relates to chiral imidodiphosphates and derivatives thereof having the general formula I, The compounds are suitable as chiral Br?nsted acid catalysts, phase-transfer catalysts, chiral anions for organic salts, metal salts or metal complexes for catalysis.