176038-84-9Relevant articles and documents
Prop-2-ynyloxybenzyloxy substituted phthalocyanine-based polymeric nanoparticles: synthesis, photophysical properties and in?vitro PDT efficacy
Xiao, Shuanghuang,Chen, Xiuqin,Ye, Qiuhao,Chen, Kuizhi,Xiao, Wenling,Guan, Xinqiao,Huang, Bingcheng,Liu, Guowei,Wei, Hui,Peng, Yiru
, p. 1232 - 1244 (2020)
Two prop-2-ynyloxybenzyloxy axially/peripherally substituted zinc/silicon phthalocyanines (YSiPc and YZnPc) were synthesized. They were encapsulated into an amphiphilic block copolymeric micelle polyethylene glycol monomethyl ether-polycaprolactone (MPEG5000–PCL2000) to form polymeric nanoparticles YSiPc@MPEG5000–PCL2000 and YZnPc@MPEG5000–PCL2000. The photophysical and photochemical properties of these polymeric nanoparticles were studied by UV/Vis and fluorescence spectroscopy. The cellular uptake and reactive oxygen species (ROS) production abilities of two polymeric nanoparticles in MCF-7 breast cancer cells were evaluated by confocal laser scanning imaging. YSiPc@MPEG5000–PCL2000 exhibited a higher cellular uptake, higher ROS generation ability as well as higher photodynamic efficacy against MCF-7 cells. YSiPc@MPEG5000–PCL2000 is a promising photosensitizer for photodynamic therapy.
Clicked (AB)2C-type miktoarm terpolymers: Synthesis, thermal and self-assembly properties, and preparation of nanoporous materials
Song, Jie,Lee, Eunji,Cho, Byoung-Ki
, p. 446 - 456 (2013)
A well-defined (PEO-PS)2-PLA miktoarm terpolymer (1) was synthesized by stepwise click reactions of individually prepared poly(ethylene oxide) (PEO), polystyrene (PS, polymerized by atom transfer radical polymerization), and polylactide (PLA, p
Supramolecular redox-responsive substrate carrier activity of a ferrocenyl Janus device
Mu, Shengdong,Ling, Qiangjun,Liu, Xiong,Ruiz, Jaime,Astruc, Didier,Gu, Haibin
, p. 31 - 41 (2019/01/24)
Supramolecular Janus compounds have recently attracted increasing attention owing to their dynamic reversible properties, distinct topological structures, and remarkable physicochemical characteristics, e.g., amphiphilicity, heterofunctionality, and high-
Direct Enzymatic Branch-End Extension of Glycocluster-Presented Glycans: An Effective Strategy for Programming Glycan Bioactivity
Bayón, Carlos,He, Ning,Deir-Kaspar, Mario,Blasco, Pilar,André, Sabine,Gabius, Hans-Joachim,Rumbero, ángel,Jiménez-Barbero, Jesús,Fessner, Wolf-Dieter,Hernáiz, María J.
supporting information, p. 1623 - 1633 (2017/02/10)
The sequence of a glycan and its topology of presentation team up to determine the specificity and selectivity of recognition by saccharide receptors (lectins). Structure–activity analysis would be furthered if the glycan part of a glycocluster could be efficiently elaborated in situ while keeping all other parameters constant. By using a bacterial α2,6-sialyltransferase and a small library of bi- to tetravalent glycoclusters, we illustrate the complete conversion of scaffold-presented lactoside units into two different sialylated ligands based on N-acetyl/glycolyl-neuraminic acid incorporation. We assess the ensuing effect on their bioactivity for a plant toxin, and present an analysis of the noncovalent substrate binding contacts that the added sialic acid moiety makes to the lectin. Enzymatic diversification of a scaffold-presented glycan can thus be brought to completion in situ, offering a versatile perspective for rational glycocluster engineering.