17607-28-2

Basic information

• Product Name: N-ACETYL-3-FLUORO-DL-PHENYLALANINE
• Synonyms: LABOTEST-BB LT00012637;N-ACETYL-3-FLUORO-DL-PHENYLALANINE;N-ACETYL-M-FLUORO-DL-PHENYLALANINE;N-acetyl-3-fluoro-3-phenyl-DL-alanine;EINECS 241-579-1;N-Acetyl-3-fluoro-DL-phenylalanine 99%;N-Acetyl-3-fluoro-DL-phenylalanine99%;(S)-2-(Acetylamino)-3-(m-fluorophenyl)propanoic acid
• CAS NO: 17607-28-2
• Molecular Formula: C₁₁H₁₂FNO₃
• Molecular Weight: 225.22
• EINECS: 241-579-1
• Mol File: 17607-28-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 154-157 °C(lit.)
• Boiling Point: 450.2 °C at 760 mmHg
• Flash Point: 226.1 °C
• Appearance: /
• Density: 1.273 g/cm³
• Vapor Pressure: 6.82E-09mmHg at 25°C
• Refractive Index: 1.532
• Storage Temp.: Keep Cold
• PKA: 3.50±0.10(Predicted)
• CAS DataBase Reference: N-ACETYL-3-FLUORO-DL-PHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ACETYL-3-FLUORO-DL-PHENYLALANINE(17607-28-2)
• EPA Substance Registry System: N-ACETYL-3-FLUORO-DL-PHENYLALANINE(17607-28-2)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 17607-28-2(Hazardous Substances Data)

Usage

Description

N-ACETYL-3-FLUORO-DL-PHENYLALANINE is a chemical compound with the molecular formula C9H10FNO3. It is a derivative of phenylalanine, an essential amino acid, where the phenylalanine molecule is modified by the addition of an acetyl group and a fluorine atom at the 3rd position. This modification may alter the compound's properties and its interactions with biological systems.

Uses

Used in Pharmaceutical Industry:
N-ACETYL-3-FLUORO-DL-PHENYLALANINE is used as a pharmaceutical compound for its neoplasm-inhibiting activity. It has potential applications in the treatment of cancer due to its ability to inhibit the growth of tumors.
Used in Cancer Treatment:
N-ACETYL-3-FLUORO-DL-PHENYLALANINE is used as an anticancer agent for its potential to inhibit the growth of various types of cancer cells. The exact mechanism of action may vary depending on the specific cancer type, but it is believed to interfere with essential cellular processes that contribute to tumor growth and progression.

InChI:InChI=1/C11H12FNO3/c1-7(14)13-10(11(15)16)6-8-3-2-4-9(12)5-8/h2-5,10H,6H2,1H3,(H,13,14)(H,15,16)

Upstream product

• 100-63-0 phenylhydrazine 
• 380-70-1 diethyl α-acetamido, α-(3-fluorobenzyl)malonate 
• 599178-62-8 C₁₁H₁₀FNO₃ 

Downstream Products

• 110117-84-5 (R)-2-amino-3-(3-fluorophenyl)propionic acid 
• 456-88-2 3-fluorophenylalanine 
• 330-45-0 N-acetyl-3-fluorophenylalanine methyl ester 
• 453-82-7 N-acetyl-3-fluoro-L-phenylalanine-(N'-phenyl-hydrazide) 
• 1132-68-9 L-4-fluorophenylalanine 
• 19883-77-3 L-3-fluorophenylalanine 

Relevant articles and documents

DEVICE AND METHOD FOR EVALUATING ORGANIC MATERIAL FOR ORGANIC SOLAR CELL

Provided are a novel 1,2-bis(dialkylphosphino)-4,5-(methylenedioxy)benzene derivative that forms a metal complex having particularly high asymmetry induction capacity and catalytic activity on β-dehydroamino acids, a method for manufacturing the same, a metal complex having this 1,2-bis(dialkylphosphino)-4,5-(methylenedioxy)benzene derivative as a ligand, and an asymmetric hydrogenation method using this metal complex. A 1,2-bis(dialkylphosphino)-4,5-(methylenedioxy)benzene derivative represented by general formula (1). (In the formula, R1 and R2 represent an alkyl group having 1-10 carbon atoms, and R1 and R2 have different numbers of carbon atoms.)

Three-hindered quadrant phosphine ligands with an aromatic ring backbone for the rhodium-catalyzed asymmetric hydrogenation of functionalized alkenes

The three-hindered quadrant phosphine ligands (R)-1-tert- butylmethylphosphino-2-(di-tert-butylphosphino)benzene ((R)-3H-BenzP*) and (R)-2-tert-butylmethylphosphino-3-(di-tert-butylphosphino)quinoxaline ((R)-3H-QuinoxP*) exhibited good to excellent enantioselectivities in the rhodium-catalyzed asymmetric hydrogenation of selected dehydroamino acid derivatives, enamides, and ethenephosphonates.

Enantiopure 1,2-Bis(tert-butylmethylphosphino)benzene as a highly efficient ligand in rhodium-catalyzed asymmetric hydrogenation

Figure Presented. An electron-rich P-stereogenic bisphosphine ligand named "BenzP" was conveniently prepared from o-dibromobenzene and enantiopure tert-butylmethylphosphine-borane. Its rhodium complex exhibited excellent enantioselectivities of up to 99.9% and high catalytic activity of up to 10000 h-1 TOF in asymmetric hydrogenations of various functionalized alkenes.