17609-80-2

Basic information

• Product Name: 4-Amino-3-chlorophenol
• Synonyms: AMINO(4-)-3-CHLOROPHENOL;4-AMINO-3-CHLOROPHENOL;3-chloro-4-aminophenol;4-amino-3-chloro-pheno;Brn 2802558;Einecs 241-583-3;Phenol, 4-amino-3-chloro-;lenvaint-G
• CAS NO: 17609-80-2
• Molecular Formula: C₆H₆ClNO
• Molecular Weight: 143.57
• EINECS: 241-583-3
• Mol File: 17609-80-2.mol
• Article Data: 17

Chemical Properties

• Melting Point: 159-160℃
• Boiling Point: 287.3°Cat760mmHg
• Flash Point: 127.6°C
• Appearance: White/Crystalline Powder
• Density: 1.406g/cm³
• Vapor Pressure: 0.00074mmHg at 25°C
• Refractive Index: 1.606
• Storage Temp.: 2-8°C(protect from light)
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 9.26±0.18(Predicted)
• CAS DataBase Reference: 4-Amino-3-chlorophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-chlorophenol(17609-80-2)
• EPA Substance Registry System: 4-Amino-3-chlorophenol(17609-80-2)

Safety Data

• RTECS: SJ5710000
• HazardClass: 6.1
• Hazardous Substances Data: 17609-80-2(Hazardous Substances Data)

Usage

Description

4-Amino-3-chlorophenol is an organic compound characterized by its light yellow solid appearance. It is known for its chemical structure that includes an amino group at the 4th position and a chlorine atom at the 3rd position on a phenol ring.

Uses

Used in Pharmaceutical Industry:
4-Amino-3-chlorophenol is used as a synthetic reagent for the preparation of Benzothiazole-based ureas. These compounds have potential as modulators for ABAD/17β-HSD10, which are targets in the treatment of Alzheimer's disease. The development of such modulators can contribute to the advancement of therapeutic strategies for this neurodegenerative condition.

InChI:InChI=1S/C6H6ClNO/c7-5-3-4(9)1-2-6(5)8/h1-3,9H,8H2

Upstream product

• 3296-07-9 1-azido-2-chlorobenzene 
• 491-11-2 3-chloro-4-nitrophenol 
• 60144-85-6 4'-acetoxy-2'-chloroacetanilide 
• 88-73-3 2-Chloronitrobenzene 
• 10468-16-3 2-chloro-N-hydroxybenzenamine 
• 74993-54-7 O-(m-chloro-phenyl)-hydroxylamine 
• 20815-53-6 4-(4-chlorophenylazo)pyridine 
• 7664-93-9 sulfuric acid 
• 7758-99-8 copper(II) sulfate 
• 7647-01-0 hydrogenchloride 
• 67-66-3 chloroform 
• 2623-33-8 4-acetoxyacetanilide 
• 7782-50-5 chlorine 
• 123-30-8 4-amino-phenol 

Downstream Products

• 695-99-8 2-Chloro-1,4-benzoquinone 
• 88680-97-1 benzenesulfonic acid-(2-chloro-4-hydroxy-anilide) 
• 122267-40-7 2-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)-ethoxy]-aniline 
• 156079-10-6 4-[Bis-(2-hydroxy-ethyl)-amino]-3-chloro-phenol 
• 156079-17-3 2-[(4-Benzyloxy-2-chloro-phenyl)-(2-hydroxy-ethyl)-amino]-ethanol 
• 156079-23-1 (4-Benzyloxy-2-chloro-phenyl)-bis-(2-chloro-ethyl)-amine 
• 172974-06-0 Carbonic acid 4-[bis-(2-chloro-ethyl)-amino]-3-chloro-phenyl ester 4-nitro-phenyl ester 
• 172974-13-9 (S)-2-{4-[Bis-(2-chloro-ethyl)-amino]-3-chloro-phenoxycarbonylamino}-pentanedioic acid dibenzyl ester 
• 122267-38-3 N-2-chlorobenzoyl-N'-2-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)-ethoxy]-phenyl-urea 
• 122267-36-1 N-(2,6-difluorobenzoyl)-N'-2-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)-ethoxy]-phenyl-urea 
• 88681-00-9 N-(2-chloro-4-oxo-cyclohexa-2,5-dienylidene)-benzenesulfonamide 
• 56074-07-8 4-acetamido-3-chlorophenol 
• 18119-24-9 8-Chlor-6-hydroxychinolin 
• 796848-80-1 phenyl N-(2-chloro-4-hydroxyphenyl)carbamate 

Relevant articles and documents

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