176107-74-7Relevant articles and documents
Synthesis and antirheumatic activity of the metabolites of esonarimod
Noguchi, Toshiya,Onodera, Akira,Tomisawa, Kazuyuki,Yamashita, Miyuki,Takeshita, Kimiyo,Yokomori, Sadakazu
, p. 2713 - 2721 (2002)
We have developed esonarimod, (±)-2-acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic acid, as a new antirheumatic drug. Now we describe herein the preparation of the enantiomers of (±)-deacetylesonarimod, the pharmaceutically active metabolites of esonar