17617-60-6

Basic information

• Product Name: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
• Synonyms: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one;7-Chloro-3-Hydroxy-5-(2-Ffluorophenyl)-1,3-Dihydro-2h-1,4-Benzodiazepine-2-One;3-hydroxy-N-desalkyl-2-oxoquazepam;()-7-CHLORO-3-HYDROXY-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPINE-2-ONE
• CAS NO: 17617-60-6
• Molecular Formula: C₁₅H₁₀ClFN₂O₂
• Molecular Weight: 304.7
• Mol File: 17617-60-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 507.1°Cat760mmHg
• Flash Point: 260.5°C
• Appearance: /
• Density: 1.48g/cm³
• Vapor Pressure: 4.18E-11mmHg at 25°C
• Refractive Index: 1.668
• CAS DataBase Reference: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one(17617-60-6)
• EPA Substance Registry System: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one(17617-60-6)

Safety Data

• Hazardous Substances Data: 17617-60-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H10ClFN2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)

Upstream product

• 89722-88-3 Trifluoro-acetic acid 7-chloro-5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl ester 
• 7435-12-3 7-Chloro-5-(2-fluoro-phenyl)-4-oxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one 

Downstream Products

• 62659-53-4 7-chloro-3-fluoro-5-(2-fluoro-phenyl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one 

Relevant articles and documents

3-FLUOROBENZODIAZEPINES

Benzodiazepines that bear a fluorine substituent in the metabolically active C-3 position were prepared by the reaction of diethylaminosulfur trifluoride (DAST) with the corresponding 3-hydroxybenzodiazepines.These products are surprisingly stable to hydrolysis and possess potent antianxiety and muscle-relaxing properties.