17629-30-0 Usage
Description
D(+)-Raffinose pentahydrate is a naturally occurring trisaccharide composed of one molecule each of D-galactose, D-glucose, and D-fructose. It is found in various vegetables and grains, and can be hydrolyzed to galactose and sucrose by α-galactosidase. D(+)-Raffinose pentahydrate is a white crystalline powder that is odorless and has a sweet taste, approximately 10% that of sucrose.
Uses
Used in the Food Industry:
D(+)-Raffinose pentahydrate is used as a prebiotic to stimulate the growth of lactobacilli and bifidobacteria, which are beneficial bacteria for gut health. It is also used as an additive in low-cariogenic food or drinks due to its non-digestible nature and lower efficiency compared to lactose or sucrose.
Used in the Cosmetics Industry:
D(+)-Raffinose pentahydrate is used as a moisturizing and smoothing agent for the skin, helping to prevent skin aging and promote skin regeneration.
Used in the Pharmaceutical Industry:
D(+)-Raffinose pentahydrate can be used in the development of pharmaceuticals, as it occurs naturally in various plant sources and has the potential for therapeutic applications.
Production Methods
Raffinose occurs naturally in Australian manna, cottonseed meal,
and seeds of various food legumes. It can be isolated from beet sugar
molasses through sucrose separation, seed-crystallization, and
filtration.
Pharmaceutical Applications
Raffinose is a trisaccharide carbohydrate that is used as a bulking
agent, blood substitute, stabilizing agent, and water scavenger in
freeze-drying where it acts as a stabilizer for freeze-dried formulations. It is also used as a crystallization inhibitor in sucrose
solutions.
Biochem/physiol Actions
Raffinose is a trisaccharide composed of galactose, fructose, and glucose. Raffinose is hydrolysed to D-galactose and sucrose by D-galactosidase.
Safety
Raffinose is a naturally occurring trisaccharide investigated for use
in freeze-dried pharmaceutical formulations. It occurs in a number
of plants that are consumed widely.
storage
Raffinose is stable under ordinary conditions of use and storage.
Excessive heat should be avoided to prevent degradation. Thermal decomposition products are carbon monoxide and carbon dioxide.
Purification Methods
fructo-furanose [17629-30-0 (5H2O), 512-69-6 (anhydrous)] M 594.5, m 8 0o, 80 -82o, +124o (c 10, H2O), [ ] D +105o (c 1 for pentahydrate, H2O), pK 1 12.40, pK 2 13.44, pK 3 13.52. D(+)-Raffinose crystallises from H2O, 90% aqueous EtOH or MeOH as the pentahydrate. The anhydrous sugar has m 132-135o. It has RF 0.8 on TLC (Silica Gel, and 1:3:3 CHCl3/butanone:/MeOH). The undecaacetate has been purified through an alumina column by elution with CHCl3, and recrystallised from EtOH/MeOH/H2O (3:2:5), with m 99-100o, [] D +92.8o (c 5.14, EtOH). [pK : Coccioli & Vicedomini Ann Chim (Rome) 66 269, 275 1976, 1H NMR: Suami et al. Carbohydr Research 26 234 1973, Beilstein 17 III/IV 3801, 17/8 V 403.]
Incompatibilities
Raffinose is incompatible with strong oxidizers.
Regulatory Status
Raffinose is a naturally occurring trisaccharide and is consumed as
part of a normal diet.
Check Digit Verification of cas no
The CAS Registry Mumber 17629-30-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,6,2 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17629-30:
(7*1)+(6*7)+(5*6)+(4*2)+(3*9)+(2*3)+(1*0)=120
120 % 10 = 0
So 17629-30-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H32O16.5H2O/c19-1-5-8(22)11(25)13(27)16(31-5)30-3-7-9(23)12(26)14(28)17(32-7)34-18(4-21)15(29)10(24)6(2-20)33-18;;;;;/h5-17,19-29H,1-4H2;5*1H2/t5?,6-,7?,8-,9+,10+,11?,12?,13?,14?,15?,16-,17+,18-;;;;;/m0...../s1
