17649-94-4

Basic information

• Product Name: 4-oxo-N,4-diphenylbutanamide
• Synonyms: 4-oxo-N,4-diphenylbutanamide;Benzenebutanamide, γ-oxo-N-phenyl-
• CAS NO: 17649-94-4
• Molecular Formula: C₁₆H₁₅NO₂
• Molecular Weight: 253.2958
• Mol File: 17649-94-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 149-150 °C(Solv: benzene (71-43-2))
• Boiling Point: 487.4±28.0 °C(Predicted)
• Appearance: /
• Density: 1.178±0.06 g/cm3(Predicted)
• PKA: 14.45±0.70(Predicted)
• CAS DataBase Reference: 4-oxo-N,4-diphenylbutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-N,4-diphenylbutanamide(17649-94-4)
• EPA Substance Registry System: 4-oxo-N,4-diphenylbutanamide(17649-94-4)

Safety Data

• Hazardous Substances Data: 17649-94-4(Hazardous Substances Data)

Upstream product

• 103-71-9 phenyl isocyanate 
• 2051-95-8 succinylbenzene 
• 142-04-1 aniline hydrochloride 
• 62-53-3 aniline 
• 1955-39-1 5-phenyl-3H-furan-2-one 
• 24244-95-9 N-Phenyl-N-succinisoimidium-perchlorat 
• 53917-82-1 β-benzoylpropionyl chloride 
• 71-43-2 benzene 
• 64-17-5 ethanol 
• 83-25-0 N-phenylmaleimide 

Downstream Products

• 33898-16-7 5-phenyl-1,3-dihydro-benzo[b]azepin-2-one 
• 6621-86-9 4-oxo-4-phenyl-butyric acid-(4-bromo-anilide) 
• 68803-52-1 4-(2-oxo-1,5-diphenyl-1,2-dihydro-pyrrol-3-ylidene)-4,N-diphenyl-butyramide 
• 26977-07-1 (+/-)-1-phenyl-4-(phenylamino)butanol 
• 77052-33-6 5-benzoyl-2-phenyl-3-isothiazolinone 
• 81470-57-7 5-benzoyl-4-chloro-2-phenyl-3-isothiazolinone 
• 134811-35-1 4-Hydroxy-4,5-diphenyl-pentanoic acid phenylamide 
• 837-56-9 1-phenyl-2-phenylpyrrole 
• 62-53-3 aniline 
• 2051-95-8 succinylbenzene 
• 74457-62-8 N-phenyl 3-benzoyl-3-bromopropionamide 
• 32559-60-7 1,5-diphenyl-3-pyrrolin-2-one 
• 21277-98-5 2-phenylisothiazol-3(2H)-one 
• 1027373-19-8 3-(2,6-Dichloro-phenyl)-5-phenyl-3a,6a-dihydro-1-oxa-6-thia-2,5-diaza-pentalen-4-one 

Relevant articles and documents

Amides in one pot from Carboxylic Acids and Amines via Sulfinylamides

An efficient method has been developed for the direct amidification of carboxylic acids via sulfinylamides preformed in situ by the reaction of pure amines with prop-2- ene-1-sulfinyl chloride. The method can be applied to aliphatic acids, including pivalic acid, aromatic acids, and primary and secondary amines. It is compatible with acids bearing unprotected alcohol, phenol, and ketone moieties and applicable to the synthesis of peptides. It does not induce their a-epimerization.

Efficient synthesis of 2-aminothiazole-4-phenyl-5-acetamides via the open chain tautomers of γ-keto amides

A simple and efficient method is described for the synthesis of new functionalized 2-aminothiazoles, the 2-aminothiazole-4-phenyl-5-acetamides 5, in 67-96% yields based on an application of the Hantzsch synthesis. The method involves the reaction of thiou

3,3'-(Phenylphosphinylidene)bis and 3,3'-(Phenylphosphinylidene)bis. New Activating Agents

New activating agents, 3,3'-(phenylphophinylidene)bis (4) and 3,3'-(phenylphosphinylidene)bis (5), were readily prepared by the reaction of phenylphosphonic dichloride (3) with 2(3H)-benzoxazolone (1) and 2(3H)-benzothiazolone (2) respectively in the presence of triethylamine at room temperature.The new activating agents 4 and 5 were found to be useful for the preparation of amides, esters, and dipeptides under mild conditions.Furthemore, the direct polycondensation of isophthalic acid with aromatic diamines using the activating agent 4 in the presence of pyridine proceeded fast at room temperature to produce polyamides with inherent viscosities up to 0.80 dL/g.