176512-49-5

Basic information

• Product Name: 2,4-diamino-5-<3,5-dimethoxy-4-<3-(3'-methyl-4'-(4''-nitrophenyl)sulfonylanilino)propoxy>benzyl>pyrimidine
• Synonyms: 2,4-diamino-5-<3,5-dimethoxy-4-<3-(3'-methyl-4'-(4''-nitrophenyl)sulfonylanilino)propoxy>benzyl>pyrimidine
• CAS NO: 176512-49-5
• Molecular Weight: 608.675
• Mol File: 176512-49-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4-diamino-5-<3,5-dimethoxy-4-<3-(3'-methyl-4'-(4''-nitrophenyl)sulfonylanilino)propoxy>benzyl>pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-diamino-5-<3,5-dimethoxy-4-<3-(3'-methyl-4'-(4''-nitrophenyl)sulfonylanilino)propoxy>benzyl>pyrimidine(176512-49-5)
• EPA Substance Registry System: 2,4-diamino-5-<3,5-dimethoxy-4-<3-(3'-methyl-4'-(4''-nitrophenyl)sulfonylanilino)propoxy>benzyl>pyrimidine(176512-49-5)

Safety Data

• Hazardous Substances Data: 176512-49-5(Hazardous Substances Data)

Upstream product

• 21253-58-7 2,4-diamino-5-(3,5-dimethoxy-4-hydroxybenzyl)pyrimidine 
• 176512-45-1 (3-Bromo-propyl)-[3-methyl-4-(4-nitro-benzenesulfonyl)-phenyl]-amine 
• 176512-36-0 N-(3-Bromo-propyl)-4-methyl-N-[3-methyl-4-(4-nitro-benzenesulfonyl)-phenyl]-benzenesulfonamide 
• 176512-31-5 4-amino-2-methyl-4'-nitrodiphenyl sulfide 
• 176512-26-8 4-Methyl-N-[3-methyl-4-(4-nitro-phenylsulfanyl)-phenyl]-benzenesulfonamide 
• 176512-23-5 3-methyl-4-(4-nitrophenylthio)aniline 

Relevant articles and documents

New antifolate 4,4'-diaminodiphenyl sulfone substituted 2,4-diamino-5-benzylpyrimidines. Proof of their dual mode of action and autosynergism

New 4,4'-diaminodiphenylsulfone substituted 2,4-diamino-5-benzylpyrimidines were synthesized. These compounds are highly active inhibitors of both bacterial dihydrofolate reductase (DHFR) and dihydropteroic acid synthase (SYN). The simultaneous inhibition