176512-50-8

Basic information

• Product Name: 2,4-diamino-5-<3,5-dimethoxy-4-<2-(4'-(2''-methyl-4''-nitrophenyl)sulfonylanilino)ethoxy>benzyl>pyrimidine
• Synonyms: 2,4-diamino-5-<3,5-dimethoxy-4-<2-(4'-(2''-methyl-4''-nitrophenyl)sulfonylanilino)ethoxy>benzyl>pyrimidine
• CAS NO: 176512-50-8
• Molecular Weight: 594.648
• Mol File: 176512-50-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4-diamino-5-<3,5-dimethoxy-4-<2-(4'-(2''-methyl-4''-nitrophenyl)sulfonylanilino)ethoxy>benzyl>pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-diamino-5-<3,5-dimethoxy-4-<2-(4'-(2''-methyl-4''-nitrophenyl)sulfonylanilino)ethoxy>benzyl>pyrimidine(176512-50-8)
• EPA Substance Registry System: 2,4-diamino-5-<3,5-dimethoxy-4-<2-(4'-(2''-methyl-4''-nitrophenyl)sulfonylanilino)ethoxy>benzyl>pyrimidine(176512-50-8)

Safety Data

• Hazardous Substances Data: 176512-50-8(Hazardous Substances Data)

Upstream product

• 176512-37-1 N-(2-Bromo-ethyl)-4-methyl-N-[4-(2-methyl-4-nitro-benzenesulfonyl)-phenyl]-benzenesulfonamide 
• 176512-32-6 4-amino-2'-methyl-4'-nitrodiphenyl sulfide 
• 176512-25-7 4-Methyl-N-[4-(2-methyl-4-nitro-phenylsulfanyl)-phenyl]-benzenesulfonamide 
• 21253-58-7 2,4-diamino-5-(3,5-dimethoxy-4-hydroxybenzyl)pyrimidine 
• 176512-46-2 (2-Bromo-ethyl)-[4-(2-methyl-4-nitro-benzenesulfonyl)-phenyl]-amine 

Relevant articles and documents

New antifolate 4,4'-diaminodiphenyl sulfone substituted 2,4-diamino-5-benzylpyrimidines. Proof of their dual mode of action and autosynergism

New 4,4'-diaminodiphenylsulfone substituted 2,4-diamino-5-benzylpyrimidines were synthesized. These compounds are highly active inhibitors of both bacterial dihydrofolate reductase (DHFR) and dihydropteroic acid synthase (SYN). The simultaneous inhibition