176671-90-2

Basic information

• Product Name: [3-(4-benzyloxy)phenoxy]benzo-[b]thiophene
• Synonyms: [3-(4-benzyloxy)phenoxy]benzo-[b]thiophene
• CAS NO: 176671-90-2
• Molecular Weight: 332.423
• Mol File: 176671-90-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: [3-(4-benzyloxy)phenoxy]benzo-[b]thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(4-benzyloxy)phenoxy]benzo-[b]thiophene(176671-90-2)
• EPA Substance Registry System: [3-(4-benzyloxy)phenoxy]benzo-[b]thiophene(176671-90-2)

Safety Data

• Hazardous Substances Data: 176671-90-2(Hazardous Substances Data)

Upstream product

• 7342-82-7 3-Bromothianaphthene 
• 103-16-2 4-Benzyloxyphenol 
• 1317-39-1 copper(I) oxide 

Downstream Products

• 205814-28-4 3-[(4-benzyloxy)phenoxy]-2-(2-hydroxyprop-2-yl) benzo[b]thiophene 
• 176672-03-0 [3-(4-benzyloxy)phenoxy]benzo[b]thiophene-2-boronic acid 

Relevant articles and documents

Benzothiphene compounds, intermediates, compositions, and methods

The invention provides benzothiophene compounds, formulations, and methods of inhibiting bone loss or bone resorption, particularly osteoporosis, and cardiovascular-related pathological conditions, including hyperlipidemia, and estrogen-dependent cancer.

Benzo[B]thiophene compounds, intermediates, processes, compositions, and methods

The instant invention provides novel benzo[b]thiophene compounds, intermediates, compositions, pharmaceutical formulations, and methods of use. The novel benzo[b] thiophenes have the formula wherein R1is -H, -OH, -O(C1-C4alkyl), -OCOAr where Ar is phenyl or substituted phenyl, -O(CO)OAr where Ar is phenyl or substituted phenyl, -OCO(C1-C6alkyl), -O(CO)O(C1-C6alkyl), or -OSO2(C4-C6alkyl); R2is -H, -F, -Cl, -OH, -O(C1-C4alkyl), -OCOAr where Ar is phenyl or substituted phenyl, -O(CO)OAr where Ar is phenyl or substitutedphenyl,-OCO(C1-C6alkyl),-O(CO)O(C1-C6alkyl), or -OSO2(C4-C6alkyl); R3and R4are, independently, -H, -F, -Cl, -CH3,-OH, -O(C1-C4alkyl), -OCOAr where Ar is phenyl or substituted phenyl, -OCO(C1-C6alkyl), -O(CO)O(C1-C6alkyl), or -OSO2(C4-C6alkyl), with the proviso that R3and R4are not both hydrogen; n is 2 or 3; and R5is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, or 1-hexamethyleneimino; ???or a pharmaceutically acceptable salt or solvate thereof.

Benzothiophene compounds, intermediates, compositions, and method for inhibiting restenosis

The present invention provides pharmaceutically active compounds of formula I STR1 wherein R1 is --H, --OH, --O(C1 -C4 alkyl), --OCOC6 H5, --OCO(C1 -C6 alkyl), or --OSO2 (C2 -C6 alkyl); R2 is --H, --OH, --O(C1 -C4 alkyl), --OCOC6 H5, --OCO(C1 -C6 alkyl), --OSO2 (C2 -C6 alkyl), or halo, providing when Z is --S--, R2 is not halo; R3 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; n is 2 or 3; and z is --O-- or --S--; or a pharmaceutically acceptable salt thereof, for inhibiting restenosis.