176791-96-1Relevant articles and documents
Ring expansion of N-acetyl aziridine-2-imides to oxazoline-4-imides, useful precursors of pure β-hydroxy α-aminoacids
Cardillo, Giuliana,Gentilucci, Luca,Tolomelli, Alessandra,Tomasini, Claudia
, p. 6953 - 6956 (2007/10/03)
Optically active N-acyl aziridine 2-imides or α-carboxylates rearrange to oxazoline-4-imides or 4-carboxylates with high regio and stereo control. This ring expansion followed by mild hydrolisis allows the synthesis of enantiomerically pure β-hydroxy α-aminoacid precursors.