177186-30-0

Basic information

• Product Name: (S)-2-((S)-1-Phenyl-ethylamino)-pent-4-enoic acid amide
• Synonyms: (S)-2-((S)-1-Phenyl-ethylamino)-pent-4-enoic acid amide
• CAS NO: 177186-30-0
• Molecular Weight: 218.299
• Mol File: 177186-30-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((S)-1-Phenyl-ethylamino)-pent-4-enoic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((S)-1-Phenyl-ethylamino)-pent-4-enoic acid amide(177186-30-0)
• EPA Substance Registry System: (S)-2-((S)-1-Phenyl-ethylamino)-pent-4-enoic acid amide(177186-30-0)

Safety Data

• Hazardous Substances Data: 177186-30-0(Hazardous Substances Data)

Upstream product

• 174506-63-9 (6R,1'S)-6-methyl-4-(1'-phenylethyl)-1,4-morpholine-2,5-dione 
• 177186-28-6 (3S,6R,1'S)-4-(1'-phenylethyl)-3-(2-propen-1-yl)-6-methyl-1,4-morpholin-2,5-dione 

Downstream Products

• 176966-58-8 (3S,5S)-5-Iodomethyl-3-((S)-1-phenyl-ethylamino)-dihydro-furan-2-one 
• 618-27-9 hydroxy L-proline 
• 81102-38-7 cis-L-hydroxyproline methyl ester 

Relevant articles and documents

Stereoselective synthesis of unnatural aminoacids cis-4-hydroxyproline and bulgecinine

A new stereoselective synthesis of both (2R,4R)- and (2S,4S)-4-hydroxy-proline and (+)- and (-)-bulgecinine was performed starting from synthons 1 or 1', respectively. The synthetic route has been established via a novel assisted cleavage of a disubstituted amide in mild conditions and successive stereocontrolled iodocyclization.