1772-65-2

Basic information

• Product Name: 4-(3-nitrophenyl)-2-oxobut-3-enoic acid
• CAS NO: 1772-65-2
• Molecular Formula: C₁₀H₇NO₅
• Molecular Weight: 221.1663
• Mol File: 1772-65-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 403.2°C at 760 mmHg
• Flash Point: 177.4°C
• Density: 1.469g/cm³
• Vapor Pressure: 3.18E-07mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: 4-(3-nitrophenyl)-2-oxobut-3-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-nitrophenyl)-2-oxobut-3-enoic acid(1772-65-2)
• EPA Substance Registry System: 4-(3-nitrophenyl)-2-oxobut-3-enoic acid(1772-65-2)

Safety Data

• Hazardous Substances Data: 1772-65-2(Hazardous Substances Data)

Upstream product

• 99-61-6 3-nitro-benzaldehyde 
• 127-17-3 2-oxo-propionic acid 
• 113-24-6 sodium pyruvate 

Downstream Products

• 1664-57-9 3-(3-nitrophenyl)propanoic acid 
• 1504-76-3 (E)-3-nitrocinnamaldehyde 
• 1772-77-6 4t-(3-nitro-phenyl)-2-oxo-but-3-enoic acid methyl ester 
• 1320256-74-3 (E)-N-(tert-butyl)-4-(3-nitrophenyl)-2-oxobut-3-enamide 
• 871335-42-1 3-([2,2′-bipyridin]-4-yl)aniline 
• 1363768-25-5 bis-{N-[3-(2,2'-dipyridin-4-yl)phenyl]}-9,18,-methano-1,8-naphthalimido[b,f][1,5]diazocene 
• 1363768-29-9 4-[N-phenyl-4-nitro-1,8-naphthalimide]-2,2’-bipyridine 
• 1363768-21-1 4-[N-(m-phenyl)-4-amino-1,8-napthalimide]-2,2'-bipyridine 
• 871335-41-0 4-(3-nitrophenyl)-2,2’-bipyridine 

Relevant articles and documents

Crystal Engineering of 6-Carboxy-4-aryl-2,2′-bipyridine Complexes: Potent Chelators with Intrinsic Intermolecular Affinity

Herein we report the coordination chemistry and structural properties of two multifunctional terdentate 2,2′-bipyridine derivatives 4- and 3-(4-nitrophenyl)-2,2′-bipyridine-6-carboxylate, L1/L2, respectively. We report eight new coordination complexes wit

Functionalisation of gold nanoparticles with ruthenium(ii) polypyridyl complexes for their application in cellular imaging

Two new dinuclear Ru(ii) polypyridyl complexes containing an alkyl disulphide functionalised bipyridine-based ligand and either 1,10-phenanthroline (phen) or 1,4,5,8-tetraazaphenanthrene (TAP) as ancillary ligands have been synthesised and characterised. Their attachment onto the surface of gold nanoparticles (AuNPs, average diameter of ca. 2.5 nm) resulted in the formation of two new water-soluble Ru(ii)-AuNP conjugates that combine the advantageous properties of both moieties. Both free complexes show the attractive photophysical properties of Ru(ii) polypyridyl complexes and a rapid cellular uptake in HeLa cervical cancer cells. However, their corresponding gold conjugates displayed lower quantum yields than those determined for the free complexes presumed to be due to an energy transfer quenching of the Ru(ii) luminescence by interaction with the gold surface. Despite their diminished luminescence, confocal fluorescence microscopy studies revealed that the Ru(ii)-AuNP conjugates are successfully internalised into HeLa cells and better tolerated than their free complex counterparts after 24 h incubation, which makes them potential luminescent nanomaterials for bioimaging applications.

Synthesis of beta-halo-gamma-aryl-alpha-hydroxy-gamma-crotonolactones of possible antineoplastic activity.

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