177201-79-5 Usage
Description
1-BOC-2,3-DIHYDRO-INDOLE-3-CARBOXYLIC ACID, also known as 1-(tert-Butoxycarbonyl)indoline-3-carboxylic acid, is a white powder chemical compound with significant applications in the pharmaceutical industry. It is primarily used in the synthesis of various bioactive molecules, including cardioselective anti-ischemic ATP-sensitive potassium channel openers and potent M2 muscarinic receptor antagonists.
Uses
Used in Pharmaceutical Industry:
1-BOC-2,3-DIHYDRO-INDOLE-3-CARBOXYLIC ACID is used as a key intermediate in the synthesis of benzopyranyl indoline analogs for their cardioselective anti-ischemic properties. These analogs act as ATP-sensitive potassium channel openers, which are crucial in the treatment of ischemic conditions in the heart.
1-BOC-2,3-DIHYDRO-INDOLE-3-CARBOXYLIC ACID is also used as a precursor in the synthesis of 1,2,3,4-tetrahydroisoquinoline derivatives. These derivatives have been identified as potent and selective M2 muscarinic receptor antagonists, which have potential applications in the treatment of various neurological and cognitive disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 177201-79-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,2,0 and 1 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 177201-79:
(8*1)+(7*7)+(6*7)+(5*2)+(4*0)+(3*1)+(2*7)+(1*9)=135
135 % 10 = 5
So 177201-79-5 is a valid CAS Registry Number.
177201-79-5Relevant articles and documents
SUBSTITUTED INDOLE DERIVATIVES
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, (2009/10/18)
The present invention relates to substituted indole derivatives having the general formula (I) which act on the ORL 1 receptor wherein A and B mutually independently denote CH2, C=O or SO2, X stands for indolyl, unsubstituted or mono- or polysubstituted; T stands for (CR5a-cR6a-c)n, n = 1, 2 or 3, and Q stands for (CR7a-cR8a-c)m, m = 0,1, 2 or 3, processes for the preparation thereof, medicinal products containing these compounds and the use of substituted indole derivatives for the preparation of medicinal products.
Carbocyclic fused cyclic amines
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Page/Page column 25-26, (2008/06/13)
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