17721-16-3

Basic information

• Product Name: 4-cyano-4-phenylhexanoic acid
• Synonyms: 4-cyano-4-phenylhexanoic acid
• CAS NO: 17721-16-3
• Molecular Weight: 217.268
• Mol File: 17721-16-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-cyano-4-phenylhexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyano-4-phenylhexanoic acid(17721-16-3)
• EPA Substance Registry System: 4-cyano-4-phenylhexanoic acid(17721-16-3)

Safety Data

• Hazardous Substances Data: 17721-16-3(Hazardous Substances Data)

Upstream product

• 539-74-2 Ethyl 3-bromopropionate 
• 769-68-6 2-phenylbutanenitrile 
• 24131-07-5 methyl 2-cyano-2-phenylbutanoate 
• 66003-76-7 Diphenyliodonium triflate 

Downstream Products

• 77-21-4 Glutethimide 
• 17575-40-5 3-ethyl-1-methyl-3-phenyl-piperidine-2,6-dione 

Relevant articles and documents

Tert-Butoxide-Mediated Arylation of 2-Substituted Cyanoacetates with Diaryliodonium Salts

A transition metal-free direct arylation of 2-substituted cyanoacetates with diaryliodonium salts was developed. With this approach, a wide range of α-tolunitrile derivatives has been synthesized in good to excellent yields of 45-92%. Furthermore, the practicability of this approach is further manifested in the synthesis of a related bioactive agent of glutarimide.