177614-69-6 Usage
Description
D-Alanine-3,3,3-d3 is a stable isotope-labeled form of D-Alanine, an amino acid predominantly found in bacterial cell walls, particularly in species like Streptococcus faecalis. It plays a crucial role in the biosynthesis of peptidoglycan crosslinking sub-units, which are vital for the structural integrity of bacterial cell walls. Additionally, D-Alanine has been observed to induce cytotoxic oxidative stress in brain tumor cells, making it a potential target for therapeutic applications.
Uses
Used in Pharmaceutical Research:
D-Alanine-3,3,3-d3 is utilized as a research tool for studying the metabolism and function of D-Alanine in various biological processes. Its stable isotope labeling allows for the tracking and quantification of D-Alanine in complex biological systems, providing valuable insights into its role in bacterial cell wall synthesis and its potential as a therapeutic target for brain tumor treatment.
Used in Antibacterial Drug Development:
D-Alanine-3,3,3-d3 serves as a key component in the development of novel antibacterial drugs targeting the biosynthesis of peptidoglycan crosslinking sub-units. By understanding the role of D-Alanine in bacterial cell wall formation, researchers can design drugs that specifically inhibit this process, leading to the disruption of bacterial cell walls and the subsequent eradication of the bacteria.
Used in Cancer Research:
In the field of cancer research, D-Alanine-3,3,3-d3 is employed as a tracer to investigate the cytotoxic oxidative stress induced by D-Alanine in brain tumor cells. This application aids in the development of targeted therapies that exploit the unique metabolic characteristics of cancer cells, potentially leading to more effective treatments for brain tumors.
Used in Analytical Chemistry:
D-Alanine-3,3,3-d3 is also used as an internal standard in analytical chemistry for the accurate quantification of D-Alanine in various samples, such as biological fluids, tissues, and cell cultures. Its stable isotopic composition ensures consistent and reliable measurements, which are crucial for the validation of experimental results and the development of new diagnostic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 177614-69-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,6,1 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 177614-69:
(8*1)+(7*7)+(6*7)+(5*6)+(4*1)+(3*4)+(2*6)+(1*9)=166
166 % 10 = 6
So 177614-69-6 is a valid CAS Registry Number.
