177665-17-7

Basic information

• Product Name: 4-phenyl-thiobutyric acid amide
• Synonyms: 4-phenyl-thiobutyric acid amide
• CAS NO: 177665-17-7
• Molecular Weight: 179.286
• Mol File: 177665-17-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-phenyl-thiobutyric acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-thiobutyric acid amide(177665-17-7)
• EPA Substance Registry System: 4-phenyl-thiobutyric acid amide(177665-17-7)

Safety Data

• Hazardous Substances Data: 177665-17-7(Hazardous Substances Data)

Upstream product

• 2046-18-6 4-phenylbutyronitrile 
• 19172-47-5 Lawessons reagent 
• 1199-98-0 4-phenylbutyramide 

Downstream Products

• 177561-41-0 4-(4-fluorophenyl)-5-(4-methylthiophenyl)-2-(3-phenylpropyl)thiazole 

Relevant articles and documents

Substituted thiazoles for the treatment of inflammation

A class of substituted thiazolyl compounds is described for use in treating inflammation disorders. Compounds are defined by Formula II STR1 wherein R1 is selected from hydrido, alkyl, haloalkyl, cyanoalkyl, alkylamino, aralkyl, arylamino, heteroarylsulfonylalkyl, heteroarylsulfonylhaloalkyl, aralkylamino, aryloxyalkyl, alkoxycarbonyl, aryl optionally substituted at a substitutable position with one or more radicals selected from halo and alkoxy, and heterocyclic optionally substituted at a substitutable position with one or more radicals selected from halo and alkyl; wherein R4 is selected from alkyl and amino; and wherein R5 is selected from aryl and heteroaryl; wherein R5 is optionally substituted at a substitutable position with one or more radicals selected from halo, alkyl and alkoxy; provided R5 is not phenyl at position 4 when R1 is α,α-bis(trifluoromethyl)methanol and R4 is methyl; or a pharmaceutically-acceptable salt thereof.