177747-94-3

Basic information

• Product Name: 2-[3-(3-bromo-phenyl)-3-oxo-propyl]-benzoic acid
• Synonyms: 2-[3-(3-bromo-phenyl)-3-oxo-propyl]-benzoic acid
• CAS NO: 177747-94-3
• Molecular Weight: 333.181
• Mol File: 177747-94-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[3-(3-bromo-phenyl)-3-oxo-propyl]-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(3-bromo-phenyl)-3-oxo-propyl]-benzoic acid(177747-94-3)
• EPA Substance Registry System: 2-[3-(3-bromo-phenyl)-3-oxo-propyl]-benzoic acid(177747-94-3)

Safety Data

• Hazardous Substances Data: 177747-94-3(Hazardous Substances Data)

Upstream product

• 55222-57-6 3-<2-(3-bromophenyl)-2-oxoethyl>-1(3H)-isobenzofuranone 
• 16859-59-9 3-hydroxy-1(3H)-isobenzofuranone 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 119-67-5 o-carboxybenzaldehyde 

Downstream Products

• 181139-72-0 methyl-[(E)]-2-[3(S)-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl] benzoate 
• 287930-77-2 (S,E)-1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol 
• 149968-11-6 methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate 
• 165896-48-0 2-[3-(3-bromo-phenyl)-3-oxo-propyl]-benzoic acid methyl ester 

Relevant articles and documents

SYNTHESIS OF LEUKOTRIENE COMPOUNDS

The present invention relates to the synthesis of leukotriene receptor agonist compounds and to novel intermediates employed in their preparation. Leukotriene agonists are used in the treatment of asthma, as well as other conditions mediated by leukotrienes such as inflammation and allergies. A compound of particular interest is montelukast and the present invention describes an improved process for making montelukast and similar compounds.