177756-64-8Relevant articles and documents
Regioselective Synthesis of 1,2- and 1,4-Dihydroquinolines by Palladium-Catalyzed Intramolecular N-Arylation
Park, Kyeong-Yong,Lee, Jinyong,Park, Seong Jun,Heo, Jung-Nyoung,Lim, Hwan Jung
, p. 3917 - 3926 (2015)
A series of 1,2- and 1,4-dihydroquinolines has been successfully prepared. The Pd-catalyzed intramolecular N-arylation of Z-enamines, formally prepared by the Horner-Wadsworth-Emmons olefination, proceeded efficiently to furnish the cyclized products. Depending on the cyclization conditions, substituted 1,4-dihydroquinolines and further isomerized 1,2-dihydroquinolines were independently obtained in high yields with an excellent control of isomerization of the double bond.
Intramolecular Anti-Carbolithiation of Alkynes: Stereo-Directing Effect of Lithium-Coordinating Substituents
Ly, Kim Uyen,Boussonnière, Anne,Castanet, Anne-Sophie
supporting information, (2022/01/19)
This paper presents the results of our investigations on the stereochemical course of intramolecular carbolithiation of alkynes. It is shown that the presence of a lithium-chelating propargylic substituent completely reverses the otherwise favored syn-pro