177900-31-1

Basic information

• Product Name: 2-Amino-4-(3,4-dimethoxy-phenyl)-6-(4-fluoro-phenyl)-nicotinonitrile
• CAS NO: 177900-31-1
• Molecular Weight: 349.364
• Mol File: 177900-31-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Amino-4-(3,4-dimethoxy-phenyl)-6-(4-fluoro-phenyl)-nicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-4-(3,4-dimethoxy-phenyl)-6-(4-fluoro-phenyl)-nicotinonitrile(177900-31-1)
• EPA Substance Registry System: 2-Amino-4-(3,4-dimethoxy-phenyl)-6-(4-fluoro-phenyl)-nicotinonitrile(177900-31-1)

Safety Data

• Hazardous Substances Data: 177900-31-1(Hazardous Substances Data)

Upstream product

• 28081-14-3 1-(4-fluorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one 
• 109-77-3 malononitrile 

Relevant articles and documents

Synthesis of some new pyrimidine bases as precursors of potential anticancer nucleosides

3,5,7-Trisubstituted-pyridopyrimidine-2,4(1H,3H)-diones (4) have been synthesized from the reaction of 2-amino-3-cyano-4,6-diarylpyridines (2) with arylisocyanates in dioxan-pyridine.Compounds 4 have also been prepared by the hydrolysis of 2 with alc.KOH to give 2-amino-3-carboxamido-4,6-disubstituted pyridines (3) which on refluxing with arylisocyanate in diphenyl ether afford 4.They are characterised by elemental analyses and IR and 1H NMR spectral data.They have been tested for antibacterial and antifungal activity.