17794-48-8

Basic information

• Product Name: 2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid
• Synonyms: ([3-(TRIFLUOROMETHYL)BENZOYL]AMINO)ACETIC ACID;2-([3-(TRIFLUOROMETHYL)BENZOYL]AMINO)ACETIC ACID;N-(3-(TRIFLUOROMETHYL)BENZOYL)GLYCINE;2-acetic acid;2-(3-(TRIFLUOROMETHYL)BENZAMIDO)ACETIC ACID ;3-trifluoromethylhippurate;m-Trifluoromethylhippuric acid;2-{[(3-trifluoromethyl)benzoyl]amino}acetic
• CAS NO: 17794-48-8
• Molecular Formula: C₁₀H₈F₃NO₃
• Molecular Weight: 247.17
• Product Categories: Aromatic Halides (substituted);Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 17794-48-8.mol
• Article Data: 11

Chemical Properties

• Melting Point: 134-138°C
• Boiling Point: 401.7°Cat760mmHg
• Flash Point: 196.7°C
• Appearance: /
• Density: 1.417g/cm³
• Vapor Pressure: 3.57E-07mmHg at 25°C
• Refractive Index: 1.497
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid(17794-48-8)
• EPA Substance Registry System: 2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid(17794-48-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 17794-48-8(Hazardous Substances Data)

Usage

General Description

2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid is a chemical compound with the molecular formula C10H9F3NO3. It is a derivative of aminoacetic acid, also known as glycine, with an added benzoyl group that has a trifluoromethyl substituent. 2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid is commonly used in pharmaceutical research as a building block for the synthesis of various pharmaceuticals. It has the potential to exhibit biological activity, particularly as an inhibitor of certain enzymes or as a ligand for specific receptors. Additionally, the trifluoromethyl group is known to enhance the biological properties of the compound, making it a valuable tool in drug development.

InChI:InChI=1/C10H8F3NO3/c11-10(12,13)7-3-1-2-6(4-7)9(17)14-5-8(15)16/h1-4H,5H2,(H,14,17)(H,15,16)

Upstream product

• 2251-65-2 3-(Trifluoromethyl)benzoyl chloride 
• 56-40-6 glycine 

Downstream Products

• 226226-39-7 N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide 
• 226226-39-7 (S)-1-(4-chlorobenzyl)-3-[N-{3-(trifluoromethyl)benzoyl}glycyl]aminopyrrolidine 
• 847956-35-8 trans-N-[(4-hydroxy-cyclohexylcarbamoyl)-methyl]-3-trifluoromethyl-benzamide 
• 847956-58-5 {(1R,3R,4S)-3-(3-methyl-butyl)-4-[2-(3-trifluoromethyl-benzoylamino)-acetylamino]-cyclohexyl}-carbamic acid tert-butyl ester 
• 845797-02-6 (2S,3S)-{3-hydroxy-2-[2-(3-trifluoromethyl-benzoylamino)-acetylamino]-hex-4-ynyl}-carbamic acid benzyl ester 
• 857650-89-6 tert-butyl [(S)-1-({[3-(Trifluoromethyl)benzoyl]amino}acetyl)pyrrolidin-3-yl]carbamate 
• 857651-12-8 N-[2-[(2R,4R)-4-Hydroxy-2-methylpyrrolidin-1-yl]-2-oxoethyl}-3-(trifluoromethyl)benzamide 
• 857651-30-0 N-{2-[(2S,4R)-4-benzyloxy-2-isopropylpyrrolidin-1-yl]-2-oxoethyl}-3-(trifluoromethyl)benzamide 
• 445478-99-9 N-[2-[[(1S,2R)-2-[(4-Chlorobenzoyl)amino]cyclopentyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide 

Relevant articles and documents

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