177966-64-2

Basic information

• Product Name: FMOC-D-4-Fluorophe
• Synonyms: (R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-(4-FLUORO-PHENYL)-PROPIONIC ACID;RARECHEM BK PT 0036;(R)-N-FMOC-4-FLUOROPHENYLALANINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-4-FLUORO-D-PHENYLALANINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-P-FLUORO-D-PHENYLALANINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-4-FLUORO-D-PHENYLALANINE;N-(9-FLUORENYLMETHOXYCARBONYL)-4-FLUOROPHENYL-D-ALANINE;N-ALPHA-FMOC-4-FLUORO-D-PHENYLALANINE
• CAS NO: 177966-64-2
• Molecular Formula: C₂₄H₂₀FNO₄
• Molecular Weight: 405.42
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;Amino Acid Derivatives;Peptide;a-amino
• Mol File: 177966-64-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 180°C
• Boiling Point: 623.9 °C at 760 mmHg
• Flash Point: 331.1 °C
• Appearance: White/Powder
• Density: 1.2642 (estimate)
• Storage Temp.: 2-8°C
• PKA: 3.75±0.10(Predicted)
• CAS DataBase Reference: FMOC-D-4-Fluorophe(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-D-4-Fluorophe(177966-64-2)
• EPA Substance Registry System: FMOC-D-4-Fluorophe(177966-64-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 177966-64-2(Hazardous Substances Data)

Usage

Description

FMOC-D-4-Fluorophe, also known as Fmoc-4-fluoro-d-phenylalanine, is an amino acid derivative characterized by its off-white powder appearance. It is a modified version of the naturally occurring amino acid phenylalanine, with a fluorine atom substitution at the 4th position. This modification grants it unique properties that make it valuable in various applications.

Uses

Used in Chemical Synthesis:
FMOC-D-4-Fluorophe is used as a building block in chemical synthesis for the creation of novel compounds with specific properties. The presence of the fluorine atom in the molecule allows for unique reactivity and selectivity in chemical reactions, making it a valuable component in the synthesis of various pharmaceuticals and specialty chemicals.
Used in Peptide Chemistry:
In peptide chemistry, FMOC-D-4-Fluorophe is utilized as a non-natural amino acid for the synthesis of modified peptides and proteins. The incorporation of this derivative can alter the properties of the resulting peptide, such as stability, solubility, and biological activity. This makes it a useful tool for the development of new therapeutic peptides and proteins with tailored characteristics.
Used in Pharmaceutical Research:
FMOC-D-4-Fluorophe is used as a key component in the development of new drugs, particularly in the field of medicinal chemistry. Its unique chemical properties allow for the design of novel drug candidates with improved pharmacokinetic and pharmacodynamic profiles. Additionally, its incorporation into drug molecules can enhance their binding affinity to target proteins, potentially leading to more effective treatments for various diseases.
Used in Material Science:
In material science, FMOC-D-4-Fluorophe can be used as a component in the development of advanced materials with specific properties. The fluorine atom in the molecule can influence the material's physical and chemical characteristics, such as its electronic properties, mechanical strength, and thermal stability. This makes it a valuable building block for the creation of new materials with applications in various industries, including electronics, aerospace, and automotive.