177966-81-3

Basic information

• Product Name: THYMOPENTIN
• Synonyms: (ASP34)-THYMOPOIETIN III (32-36) (BOVINE);ARG-LYS-ASP-VAL-TYR;H-ARG-LYS-ASP-VAL-TYR-OH;THYMOPENTIN 5;THYMOPOIETIN (32-36) (HUMAN, MOUSE);THYMOPOIETIN II FRAGMENT (32-36);THYMOPOIETIN I/II (32-36) (BOVINE);THYMOPOIETIN PENTAPEPTIDE
• CAS NO: 177966-81-3
• Molecular Formula: C30H49N9O9
• Molecular Weight: 679.76
• Product Categories: Various Peptides;hormones
• Mol File: 177966-81-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: THYMOPENTIN(CAS DataBase Reference)
• NIST Chemistry Reference: THYMOPENTIN(177966-81-3)
• EPA Substance Registry System: THYMOPENTIN(177966-81-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 177966-81-3(Hazardous Substances Data)

Usage

General Description

THYMOPENTIN is a synthetic and modified version of a naturally occurring thymus hormone, thymosin alpha 1, which plays a key role in immune system regulation. This chemical has been investigated for its potential in enhancing the body's immune response and is often used as a treatment for various immune deficiencies and diseases, such as hepatitis B and C, and as an adjuvant therapy in cancer treatment. THYMOPENTIN is administered through subcutaneous injections and has been shown to stimulate the production of immune cells and cytokines, leading to improved immune function and better response to infections and diseases. However, further research is required to fully understand and harness the potential therapeutic benefits of THYMOPENTIN.

Upstream product

• 127290-80-6 C₆₂H₇₃N₉O₁₇ 
• 64-19-7 acetic acid 
• 75957-57-2 N^α-benzyloxycarbonyl-N^ω-nitro-L-arginyl-N^α-benzyloxycarbonyl-L-lysyl-β-benzyl-L-aspartyl-L-valyl-L-tyrosine benzyl ester 
• 58810-10-9 Z-L-Arg(Mbs)-OH 
• 10512-93-3 Z-Val-ONp 
• 1155-64-2 N₆-[(benzyloxy)carbonyl]-L-lysine 
• 15149-72-1 N-(N-benzyloxycarbonyl-L-valyl)-L-tyrosine methyl ester 
• 54244-58-5 Valyl-tyrosine Methyl Ester 
• 14611-35-9 N^α,N^G,N^G-tri-Z-arginine p-nitrophenylester 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 75958-14-4 Aspartyl-valyl-tyrosine 
• 80622-02-2 tris(carbobenzyloxy)-L-arginyl-N^ε-(carbobenzyloxy)-L-lysine 
• 127290-79-3 pentafluorophenyl ester of N^α,N^G,N^G-tribenzyloxycarbonylarginyl0N^ε-benzyloxycarbonyllysine 

Relevant articles and documents

IMMUNOACTIVE PEPTIDES. I. SYNTHESIS OF ACTIVE FRAGMENTS OF SOME PEPTIDE HORMONES ON THE THYMUS

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Conventional Synthesis of Thymopoietin 32-36 (TP 5) Using the 1-(1-Adamantyl)-1-methyletoxycarbonyl Group

A synthesis of high yields of TP 5 is described.The α-amino functions were blocked by the acid-labile 1-(1-adamantyl)-1-methylethoxycarbonyl-(Adpoc)group.The Adpoc group is cleaved under mild acidolytic conditions with 3percent TFA in CH2Cl2 while the tert-butyl residues remained intact.This selective cleavage of the Adpoc group compared with the Boc and tert-butyl residues allows new strategies for the synthesis of large peptides. - Keywords: Adpoc, Amino acids, Thymopoietin