177980-10-8 Usage
General Description
Uridine, 2'-azido-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- is a modified form of uridine, a nucleoside in RNA. This specific chemical compound has a 2'-azido-5'-O-[bis(4-methoxyphenyl)phenylmethyl] group attached to the 2'-deoxyribose moiety of uridine. This modification alters the structure and properties of the molecule, potentially impacting its biological activity and interactions. The compound may be used in research and pharmaceutical development for studying nucleic acid structures, modifying RNA function, or developing new drugs. Additionally, it could have potential applications in the development of nucleoside analogs for antiviral or anticancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 177980-10-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,9,8 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 177980-10:
(8*1)+(7*7)+(6*7)+(5*9)+(4*8)+(3*0)+(2*1)+(1*0)=178
178 % 10 = 8
So 177980-10-8 is a valid CAS Registry Number.
177980-10-8Relevant articles and documents
A direct comparison of azide and nitrile vibrational probes
Gai, Xin Sonia,Coutifaris, Basil A.,Brewer, Scott H.,Fenlon, Edward E.
, p. 5926 - 5930 (2011)
The synthesis of 2′-azido-5-cyano-2′-deoxyuridine, N 3CNdU (1), from trityl-protected 2′-amino-2′-deoxyuridine was accomplished in four steps with a 12.5% overall yield. The IR absorption positions and profiles of the azide and nitrile group of
Chemical synthesis of site-specifically 2'-azido-modified RNA and potential applications for bioconjugation and RNA interference
Aigner, Michaela,Hartl, Markus,Fauster, Katja,Steger, Jessica,Bister, Klaus,Micura, Ronald
, p. 47 - 51 (2012/11/07)
-
Synthesis of functionalised nucleosides for incorporation into nucleic acid-based serine protease mimics
Catry, Mieke A.,Madder, Annemieke
, p. 114 - 129 (2008/02/04)
The synthesis of nucleosides modified with an extra imidazole, carboxyl and hydroxyl group is described. These nucleosides can be incorporated into an oligonucleotide duplex, thus generating a novel type of serine protease mimic.