178381-05-0Relevant articles and documents
Catalytic asymmetric synthesis of β-fluoroalkyl-β-amino acids via biomimetic [1,3]-proton shift reaction
Soloshonok, Vadim A.,Kirilenko, Alexander G.,Galushko, Sergey V.,Kukhar, Valery P.
, p. 5063 - 5064 (2007/10/02)
[1,3]-Proton shift reaction of N-benzylenamines 1a-e, derived from β- polyfluoroalkyl-β-ketocarboxylic esters and benzylamine, was catalyzed by (- )-cinchonidine (5-13 mol %) to give good yields (67-89%) of enantiomerically enriched (up to 36% ee) N-benzy