178392-67-1

Basic information

• Product Name: 2-amino-6-(N-benzyl-N-3-butynylamino)-4-chloro-5-formylpyrimidine
• Synonyms: 2-amino-6-(N-benzyl-N-3-butynylamino)-4-chloro-5-formylpyrimidine
• CAS NO: 178392-67-1
• Molecular Weight: 314.774
• Mol File: 178392-67-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-6-(N-benzyl-N-3-butynylamino)-4-chloro-5-formylpyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-6-(N-benzyl-N-3-butynylamino)-4-chloro-5-formylpyrimidine(178392-67-1)
• EPA Substance Registry System: 2-amino-6-(N-benzyl-N-3-butynylamino)-4-chloro-5-formylpyrimidine(178392-67-1)

Safety Data

• Hazardous Substances Data: 178392-67-1(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 5604-46-6 2-amino-4,6-dichloropyrimidine-5-carboxaldehyde 
• 107301-61-1 N-benzyl-4-amino-1-butyne 

Downstream Products

• 178392-69-3 N-[4-(Benzyl-but-3-ynyl-amino)-5-formyl-6-methoxy-pyrimidin-2-yl]-2,2-dimethyl-propionamide 
• 178392-68-2 2-amino-6-(N-benzyl-N-3-butynylamino)-5-formyl-4-methoxypyrimidine 

Relevant articles and documents

Synthesis of 5-amino-9-benzyl-6-formyl-4-methoxy-2-pivaloylamino-7,8-dihydropyrimido[4,5-b] azepine. A potentially useful intermediate towards the synthesis of pyrimidoazepine based folic acid derivatives

Synthesis of the title compound is described via an intramolecular 1,3-dipolar cycloaddition reaction between the pyrimidine nitrile oxide 24 and an alkyne dipolarophile tethered to the 6-position of the pyrimidine ring. The resulting isoxazolopyrimidoaze