178406-02-5Relevant articles and documents
Synthesis and reactivity of aldehydes of the adamantane series
Voloboev,Butenko,Novakov
, p. 1121 - 1125 (2007/10/03)
1-Adamantanecarbonitriles are very active in the Stephen reaction, which allows synthesis of the corresponding aldehydes in high yields. Electron-acceptor substituents in the 3 position of the adamantine nucleus exert almost no effect on the yield of aldehydes. Separation of the nitrile group and the adamantane nucleus by one methylene group results in a complete loss of reactivity. A quantitative study of the reactivity of the synthesized aldehydes in the oximation reaction was performed.
