178421-57-3

Basic information

• Product Name: (S)-N-tert-Butyl-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-methyl-butyramide
• Synonyms: (S)-N-tert-Butyl-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-methyl-butyramide
• CAS NO: 178421-57-3
• Molecular Weight: 302.373
• Mol File: 178421-57-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-N-tert-Butyl-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-methyl-butyramide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-tert-Butyl-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-methyl-butyramide(178421-57-3)
• EPA Substance Registry System: (S)-N-tert-Butyl-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-methyl-butyramide(178421-57-3)

Safety Data

• Hazardous Substances Data: 178421-57-3(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 

Downstream Products

• 3057-81-6 (S)-2-amino-N-tert-butyl-3-methylbutanamide 

Relevant articles and documents

Chiral calcium catalysts for asymmetric hydroamination/cyclisation

Calcium complexes supported by chiral 1,2-diamines have been shown to be efficient catalysts for the asymmetric hydroamination of amino-olefin substrates; the calcium complexes [Ca(NNR){N(SiMe3) 2}(THF)] (R = tBu, iPr, Ph, 4-C 6H4F) give enantioselectivities of up to 26% which marks a significant increase based upon literature precedence. The structure of [Ca(NNPh){N(SiMe3)2}(py)] has been computed with density functional methods.