178484-42-9

Basic information

• Product Name: (S)-5-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-1-methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester
• Synonyms: (S)-5-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-1-methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester
• CAS NO: 178484-42-9
• Molecular Weight: 580.572
• Mol File: 178484-42-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-5-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-1-methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-1-methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester(178484-42-9)
• EPA Substance Registry System: (S)-5-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-1-methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester(178484-42-9)

Safety Data

• Hazardous Substances Data: 178484-42-9(Hazardous Substances Data)

Upstream product

• 138279-21-7 (R)-1-Methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid mono-(2,2-dimethyl-propionyloxymethyl) ester 
• 138299-10-2 bis(pivaloyloxymethyl) 1,4-dihydro-1-(methoxymethyl)-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate 
• 1005-69-2 2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 
• 178484-39-4 (S)-5-Bromo-1-methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester 

Downstream Products

• 111495-26-2 (S)-5-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 

Relevant articles and documents

Asymmetric synthesis of (S)-(+)- and (R)-(-)-NZ-105 through the modified Michaelis-Arbuzov rearrangement as a key step

The asymmetric synthesis of the (S)-(+)- and (R)-(-)-NZ-105 from the prochiral compound (1) was realized by using the modified Hunsdiecker reaction followed by the modified Michaelis-Arbuzov reaction with zerovalent palladium.