178556-69-9

Basic information

• Product Name: (E)-4-(naphthalene-2-yl)but-3-enoic acid
• Synonyms: (E)-4-(naphthalene-2-yl)but-3-enoic acid
• CAS NO: 178556-69-9
• Molecular Weight: 212.248
• Mol File: 178556-69-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-4-(naphthalene-2-yl)but-3-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(naphthalene-2-yl)but-3-enoic acid(178556-69-9)
• EPA Substance Registry System: (E)-4-(naphthalene-2-yl)but-3-enoic acid(178556-69-9)

Safety Data

• Hazardous Substances Data: 178556-69-9(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 2489-87-4 2-allylnaphthalene 

Downstream Products

• 164295-93-6 methyl 5-(naphthalen-2-yl)-1H-pyrazole-3-carboxylate 
• 178556-70-2 4-(1-Trityl-1H-imidazol-4-yl)-1,2,3,4-tetrahydro-phenanthren-4-ol 
• 782-28-5 4-(2-naphthyl)butyric acid 

Relevant articles and documents

Cobalt-Catalyzed Allylic C(sp3)-H Carboxylation with CO2

Catalytic carboxylation of the allylic C(sp3)-H bond of terminal alkenes with CO2 was developed with the aid of a Co/Xantphos complex. A wide range of allylarenes and 1,4-dienes were successfully transformed into the linear styrylacetic acid and hexa-3,5-dienoic acid derivatives in moderate to high yields, with excellent regioselectivity. The carboxylation showed remarkable functional group tolerability, so that selective addition to CO2 occurred in the presence of other carbonyl groups such as amide, ester, and ketone. Since styrylacetic acid derivatives can be readily converted into optically active γ-butyrolactones through Sharpless asymmetric dihydroxylation, this allylic C(sp3)-H carboxylation showcases a facile synthesis of γ-butyrolactones from simple allylarenes via short steps.