17887-55-7Relevant articles and documents
A ONE-POT ORTHO ALKYLATION OF AROMATIC ALDEHYDES
Comins, Daniel L.,Brown, Jack D.,Mantlo, Nathan B.
, p. 3979 - 3982 (1982)
The addition of aromatic aldehydes to lithium N-methylpiperazide in benzene gave α-amino alkoxides which were ortho-lithiated with excess n-butyllithium.Subsequent alkylation and hydrolysis provided ortho-substituted aromatic aldehydes via a one-pot reaction.
Internal Lewis acid assisted ureas: Tunable hydrogen bond donor catalysts
Nickerson, David M.,Angeles, Veronica V.,Auvil, Tyler J.,So, Sonia S.,Mattson, Anita E.
supporting information, p. 4289 - 4291 (2013/06/04)
The strategic incorporation of internal Lewis acids onto urea scaffolds gives rise to a family of tunable hydrogen bond donor catalysts. The nature of the Lewis acid and associated ligands affects the urea polarization, acidity, and activity in reactions
Internal Lewis acid assisted benzoic acid catalysis
Auvil, Tyler J.,Mattson, Anita E.
supporting information; experimental part, p. 2173 - 2180 (2012/09/22)
Internal Lewis acid assisted benzoic acid derivatives are introduced as new low-molecular-weight single-hydrogen-bond donor catalysts for the activation of nitroalkenes. Selected 2-borylbenzoic acid derivatives gave good yields of products in the addition of indoles to nitroalkenes. Control experiments suggest that both the internal Lewis acid coordination and the carboxylic acid functionalities are critical to the optimal performance of these catalysts. Georg Thieme Verlag Stuttgart New York.
