178912-62-4 Usage
Description
9-Piperazino Levofloxacin is a degradation product of Levofloxacin (L360000), which is a fluoroquinolone antibiotic used to treat a variety of bacterial infections. It is characterized by its piperazine moiety, which is a common structural feature in many fluoroquinolones, contributing to their antibacterial activity.
Uses
Used in Pharmaceutical Industry:
9-Piperazino Levofloxacin is used as a Levofloxacin impurity for the purpose of quality control and assurance in the manufacturing process of Levofloxacin. It helps in the development of analytical methods to identify and quantify impurities in the final drug product, ensuring the safety, efficacy, and purity of the antibiotic.
Additionally, understanding the degradation products like 9-Piperazino Levofloxacin can aid in the stability testing of Levofloxacin, which is crucial for its shelf life and overall performance as a pharmaceutical agent.
Check Digit Verification of cas no
The CAS Registry Mumber 178912-62-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,9,1 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 178912-62:
(8*1)+(7*7)+(6*8)+(5*9)+(4*1)+(3*2)+(2*6)+(1*2)=174
174 % 10 = 4
So 178912-62-4 is a valid CAS Registry Number.
178912-62-4Relevant articles and documents
Preparation method of ofloxacin impurity D
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Paragraph 0022; 0031; 0032, (2018/04/02)
The invention discloses a preparation method of ofloxacin impurity D, and belongs to the field of medicine synthesis. The preparation method has the advantages that the whole technology design is reasonable, the operability is strong, and the purifying is convenient. The preparation method is characterized in that oxygen-fluorine acid is used as an initiating raw material, and is performed with six-step reaction, so as to synthesize the ofloxacin impurity D. The ofloxacin impurity D prepared by the preparation method has the advantages that by screening the optimum preparation steps and reaction conditions through experiment, the purity can reach 99.5% or above; a testing sample is provided for the study of ofloxacin, and the important study value is realized in the clinical pharmacokinetic study.
