179113-54-3Relevant articles and documents
Substituted coumarins as potent 5-lipoxygenase inhibitors
Grimm, Erich L.,Brideau, Christine,Chauret, Nathalie,Chan, Chi-Chung,Delorme, Daniel,Ducharme, Yves,Ethier, Diane,Falgueyret, Jean-Pierre,Friesen, Richard W.,Guay, Jocelyne,Hamel, Pierre,Riendeau, Denis,Soucy-Breau, Chantal,Tagari, Philip,Girard, Yves
, p. 2528 - 2531 (2007/10/03)
Leukotriene biosynthesis inhibitors have potential as therapeutic agents for asthma and inflammatory diseases. A novel series of substituted coumarin derivatives has been synthesized and the structure-activity relationship was evaluated with respect to th