179421-15-9

Basic information

• Product Name: 4-cyano-4-{3-[tri-(1-methylethyl)]silylthiophenyl}-3,4,5,6-tetrahydro-2H-pyran
• CAS NO: 179421-15-9
• Molecular Weight: 375.651
• Mol File: 179421-15-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-cyano-4-{3-[tri-(1-methylethyl)]silylthiophenyl}-3,4,5,6-tetrahydro-2H-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyano-4-{3-[tri-(1-methylethyl)]silylthiophenyl}-3,4,5,6-tetrahydro-2H-pyran(179421-15-9)
• EPA Substance Registry System: 4-cyano-4-{3-[tri-(1-methylethyl)]silylthiophenyl}-3,4,5,6-tetrahydro-2H-pyran(179421-15-9)

Safety Data

• Hazardous Substances Data: 179421-15-9(Hazardous Substances Data)

Upstream product

• 130723-54-5 (3-iodophenyl)acetonitrile 
• 179421-14-8 4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran 
• 156275-96-6 triisopropylsilanethiol 

Downstream Products

• 179420-17-8 4-[3-[4-(2-methylimidazol-1-yl)phenylthio]phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide 
• 278183-73-6 4-cyano-4-{3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]}phenyl-3,4,5,6-tetrahydro-2H-pyran 

Relevant articles and documents

Optimization of imidazole 5-lipoxygenase inhibitors and selection and synthesis of a development candidate

Structural modification of imidazole 5-lipoxygenase (5-LO) inhibitors for optimizing inhibitory potency, pharmacokinetic behavior and toxicity (ocular) profile led to 4-{3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]}phenyl-3,4,5,6- tetrahydro-2H-pyran-4-car