179487-70-8

Basic information

• Product Name: methyl 2-(1H-indol-1-yl)benzoate
• Synonyms: methyl 2-(1H-indol-1-yl)benzoate
• CAS NO: 179487-70-8
• Molecular Weight: 251.285
• Mol File: 179487-70-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: methyl 2-(1H-indol-1-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(1H-indol-1-yl)benzoate(179487-70-8)
• EPA Substance Registry System: methyl 2-(1H-indol-1-yl)benzoate(179487-70-8)

Safety Data

• Hazardous Substances Data: 179487-70-8(Hazardous Substances Data)

Upstream product

• 88-67-5 2-Iodobenzoic acid 
• 120-72-9 indole 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 25660-62-2 2-(1H-indol-1-yl)benzoic acid 
• 74-88-4 methyl iodide 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 17763-70-1 methyl 2-(trifluoromethylsulfonyloxy)benzoate 

Downstream Products

• 1146543-37-4 1-[2-(2,2-dibromo-vinyl)-phenyl]-1H-indole 
• 25660-62-2 2-(1H-indol-1-yl)benzoic acid 
• 179487-71-9 2-indolylbenzyl alcohol 

Relevant articles and documents

Synthesis of Axially Chiral Olefin-Oxazoline Ligands via Pd-Catalyzed Multiple C-H Functionalization

We report herein the Pd-catalyzed oxazoline-directed C-H olefination of the N-arylindole skeleton, affording two diastereomers of axially chiral olefin-oxazoline ligands in a one-step procedure. Modifications at the 3- and 3′-positions were facilely achieved via electrophilic substitution of the indole fragment and subsequent oxazoline-directed C-H amidation or olefination of the arene fragment.

Isocyanide-Induced Activation of Copper Sulfate: Direct Access to Functionalized Heteroarene Sulfonic Esters

A novel and direct approach to alkyl/aryl heteroarene sulfonic esters using copper sulfate as the environmentally benign inorganic sulfonation reagent was first realized with the aid of isocyanide. A variety of heterocycles reacted to afford the corresponding sulfonic esters through C?H functionalization. In this transformation, the otherwise inert copper sulfate was unusually activated by an isocyanide and employed as the source of the sulfonic substituents in an unprecedented fashion. The findings suggest that an appropriate activator may liberate the chemical activities of some relatively inert inorganic salts for organic synthesis.

Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one derivatives

The hitherto unknown lactone 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one and six of its substituted derivatives have been prepared by active manganese dioxide promoted oxidative cyclization of the corresponding 2-(1H-pyrrol-1-yl)benzoic acids, under mild conditions, in moderate yields. The method was successfully extended to the cyclization of some ortho-(1H-pyrrol-1-yl)heteroaryl carboxylic acids and 2-(1H-indol-1-yl)benzoic acids.