17952-96-4

Basic information

• Product Name: 3,5-diphenyl-4H-pyrazol-4-one 1,2-dioxide
• CAS NO: 17952-96-4
• Molecular Formula: C₁₅H₁₀N₂O₃
• Molecular Weight: 266.2515
• Mol File: 17952-96-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 472.5°C at 760 mmHg
• Flash Point: 236.1°C
• Density: 1.37g/cm³
• Vapor Pressure: 4.24E-09mmHg at 25°C
• Refractive Index: 1.69
• CAS DataBase Reference: 3,5-diphenyl-4H-pyrazol-4-one 1,2-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-diphenyl-4H-pyrazol-4-one 1,2-dioxide(17952-96-4)
• EPA Substance Registry System: 3,5-diphenyl-4H-pyrazol-4-one 1,2-dioxide(17952-96-4)

Safety Data

• Hazardous Substances Data: 17952-96-4(Hazardous Substances Data)

Usage

General Description

3,5-diphenyl-4H-pyrazol-4-one 1,2-dioxide is a chemical compound with the molecular formula C15H10N2O3. It is a derivative of pyrazolone and contains two phenyl groups attached to the pyrazolone ring. 3,5-diphenyl-4H-pyrazol-4-one 1,2-dioxide has been studied for its potential applications in the field of organic synthesis and medicinal chemistry. It has also been investigated for its antioxidant and antimicrobial properties. Additionally, 3,5-diphenyl-4H-pyrazol-4-one 1,2-dioxide has shown potential as a promising scaffold for the development of new pharmaceutical drugs. Overall, this compound has generated interest for its diverse range of potential applications in various scientific fields.

Upstream product

• 21067-42-5 1,3-diphenyl-2-propen-1-one oxime 

Downstream Products

• 71964-78-8 1-oxy-2,3a-diphenyl-7a-piperidin-1-yl-3b,4,5,6,7,7a-hexahydro-3aH-benzo[d]pyrazolo[1,5-b]isoxazol-3-one 
• 71964-81-3 1-oxy-2,3a-diphenyl-7a-pyrrolidin-1-yl-3b,4,5,6,7,7a-hexahydro-3aH-benzo[d]pyrazolo[1,5-b]isoxazol-3-one 
• 71964-79-9 7a-morpholin-4-yl-1-oxy-2,3a-diphenyl-3b,4,5,6,7,7a-hexahydro-3aH-benzo[d]pyrazolo[1,5-b]isoxazol-3-one 
• 26732-98-9 2-butoxy-6-oxy-3a,5-diphenyl-3,3a-dihydro-2H-pyrazolo[1,5-b]isoxazol-4-one 
• 26732-97-8 4-oxo-6-oxy-3a,5-diphenyl-2,3,3a,4-tetrahydro-pyrazolo[1,5-b]isoxazole-2-carboxylic acid methyl ester 
• 144951-17-7 C₂₅H₁₈N₂O₄ 
• 49661-64-5 dimethyl (1-methyl-3,5-diphenyl-4-pyrazolyl)phosphate 
• 35228-99-0 3,5-diphenyl-1-methyl-4-pyrazolol 
• 34765-45-2 1-methyl-3,5-diphenyl-4-acetoxypyrazole 

Relevant articles and documents

Preparation of 4-Bromo-1-hydroxypyrazole 2-Oxides by Nitrosation of α-Bromo-α,β-unsaturated Ketoximes

Nitrosation of the oximes of 3-bromo-3-penten-2-one, 3-bromo-4-phenyl-3-buten-2-one, and 2-bromo-1,3-diphenyl-2-propen-1-one using sodium nitrite in acetic acid gave low yields of 4-pyrazolone 1,2-dioxides.Nitrosation using butyl nitrite in the presence of copper(II) sulfate and pyridine in aqueous ethanol produced insoluble copper complexes from which 3,5-dimethyl-, 3-methyl-5-phenyl-, and 3,5-diphenyl-4-bromo-1-hydroxypyrazole 2-oxides could be liberated by treatment with dilute potassium hydroxide, filtration, and acidification of the filtrate.High yields wereobtained with the first two oximes, but, presumably due to unfavorable stereochemistry of the oxime, the diphenyl derivative gave a lower yield of the complex, accompanied by 4-bromo- and 4-nitro-3,5-diphenylisoxazole and 4-oximino-3,5-diphenyl-4,5-dihydroisoxazole.

Nitrosation of Methyl and Phenyl Styryl Ketoximes Under Oxygen. Formation of 4-Nitro-1-hydroxypyrazole 2-Oxides and 3,5-Diphenyl-4-nitrato-4,5-dihydroisoxazole

The nitrosation of the oximes of 4-phenyl-3-buten-2-one and 1,3-diphenyl-2-propen-1-one under oxygen has been reinvestigated.In addition to 4-oxo- and 4-oximino-4H-pyrazole 1,2-dioxides previously reported, the reactions give 4-nitro-1-hydroxypyrazole 2-oxides.In the case of 1,3-diphenyl-2-propen-1-one oxime the nitrosation reaction also gives 3,5-diphenyl-4-nitrato-4,5-dihydroisoxazole.Evidence is presented suggesting that the nitrate ester is formed through the rearrangement of a peroxynitrite intermediate.