179532-60-6

Basic information

• Product Name: benzyl (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoate
• Synonyms: benzyl (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoate
• CAS NO: 179532-60-6
• Molecular Weight: 514.689
• Mol File: 179532-60-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: benzyl (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoate(179532-60-6)
• EPA Substance Registry System: benzyl (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoate(179532-60-6)

Safety Data

• Hazardous Substances Data: 179532-60-6(Hazardous Substances Data)

Upstream product

• 1042432-14-3 benzyl (3aS,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-4-hydroxyl-1H-thieno[3,4-d]imidazol-4-yl)pentanoate 
• 1042432-15-4 benzyl (3aS,4Z,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-ylidene)pentanoate 
• 100-39-0 benzyl bromide 
• 58-85-5 biotin 

Downstream Products

• 58-85-5 biotin 
• 942121-51-9 1,3-dibenzyl-6-(5-hydroxy-pentyl)-5,5-dioxo-hexahydro-5λ⁶-thieno[3,4-d]imidazol-2-one 
• 942121-50-8 5-(1,3-dibenzyl-2,5,5-trioxo-octahydro-5λ⁶-thieno[3,4-d]imidazol-6-yl)pentanoic acid benzyl ester 
• 179532-65-1 1,3-dibenzyl-6-(5-hydroxy-pentyl)-tetrahydro-thieno[3,4-d]imidazol-2-one 

Relevant articles and documents

PROCESS FOR THE MANUFACTURE OF (+)-BIOTIN

Disclosed are processes for preparing synthetic biotin intermediates and a process for preparing biotin using said intermediates. In particular, disclosed is a process for the stereoselective total synthesis of the natural product (+)-biotin of formula (I).

An efficient epimerization of biotin sulfone derivatives to 2-epi-biotin analogs

Reduction of biotin sulfone derivatives leads to 2-epi-biotin analogs. The stereochemistry of the side chain at C2 can be simply deduced from the diagnostic chemical shift pattern of the benzylic protons, rather than through the conventional an